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Knowing origin of broadly neutralizing antibodies could aid universal flu vaccine design

National Institutes of Health scientists have identified how a kind of immature immune cell responds to a part of influenza virus and have traced the path those cells take to generate antibodies that can neutralize a wide ...

Medical research created Aug 29, 2012 | popularity not rated yet | comments 0 | with audio podcast

Belimumab for lupus erythematosus: Added benefit not proven

Belimumab (trade name Benlysta) has been approved since July 2011 as an add-on therapy for adult patients with the autoimmune disease systemic lupus erythematosus (SLE). This monoclonal antibody is only considered as treatment ...

Cancer created Aug 29, 2012 | popularity not rated yet | comments 0

New hope for spinal cord injury patients

A new antibody could reverse the damage caused by trauma to the central nervous system, according to new research.

Diseases, Conditions, Syndromes created Aug 29, 2012 | popularity 3 / 5 (1) | comments 0

Double attack on SARS

After the SARS-CoV (severe acute respiratory syndrome coronavirus) outbreak in 2003, academia experts in immunology and molecular biology joined forces with industrial vaccine production experts in order ...

Diseases, Conditions, Syndromes created Aug 28, 2012 | popularity not rated yet | comments 0

Targeting sugars in the quest for a vaccine against HIV -- the virus that causes AIDS

As a step toward designing the first effective vaccine against HIV, the virus that causes AIDS, scientists are reporting new insights into how a family of rare, highly potent antibodies bind to HIV and neutralize it — ...

HIV & AIDS created Aug 21, 2012 | popularity not rated yet | comments 0

Dual action polyclonal antibody may offer more effective, safer protection against osteoporosis

A new study suggests that a polyclonal antibody that blocks follicle-stimulating hormone (FSH) in mice without ovaries might offer a more effective way to prevent or arrest osteoporosis than currently available treatments.

Medical research created Aug 20, 2012 | popularity 5 / 5 (1) | comments 0 | with audio podcast

Mepolizumab almost halves exacerbations in patients with severe asthma

The largest study of patients with severe asthma to date, published in the Lancet special issue on respiratory medicine, shows that those treated with the monoclonal antibody mepolizumab experienced an almost 50 percent reduct ...

Immunology created Aug 16, 2012 | popularity not rated yet | comments 0

Blood markers reveal severity of common kidney disease

Increasing blood levels of particular proteins may act as warning signs for patients with one of the most common diseases of the kidney, according to a study appearing in an upcoming issue of the Journal of the American So ...

Diseases, Conditions, Syndromes created Aug 16, 2012 | popularity not rated yet | comments 0

Study suggests potential hurdle to universal flu vaccine development may be overcome

In the quest for a universal influenza vaccine—one that elicits broadly neutralizing antibodies that can protect against most or all strains of flu virus—scientists have faced a sobering question: Does pre-existing ...

Diseases, Conditions, Syndromes created Aug 15, 2012 | popularity not rated yet | comments 0 | with audio podcast

Blood cancer cells initiate signalling cascade

Researchers in the group of Prof. Dr. Hassan Jumaa, Centre for Biological Signalling Studies (BIOSS) of the University of Freiburg, Department for Molecular Immunology, have identified a new mechanism that ...

Cancer created Aug 13, 2012 | popularity not rated yet | comments 0

Hepatitis A vaccination in children under two remains effective for ten years

Vaccination against the hepatitis A virus (HAV) in children two years of age and younger remains effective for at least ten years, according to new research available in the August issue of Hepatology, a journal of the Am ...

Diseases, Conditions, Syndromes created Aug 09, 2012 | popularity 5 / 5 (1) | comments 0 | with audio podcast

Toward 'universal' vaccine: Scientists describe antibodies that protect against large variety of flu viruses

A team led by scientists at The Scripps Research Institute and Crucell Vaccine Institute in the Netherlands describes three human antibodies that provide broad protection against Influenza B virus strains. ...

Medical research created Aug 09, 2012 | popularity 5 / 5 (5) | comments 0 | with audio podcast

Gum disease four times as common in rheumatoid arthritis patients

Gum disease is not only four times as common among patients with the autoimmune disease rheumatoid arthritis as it is among their healthy peers, but it also tends to be more severe, indicates a small study published online ...

Arthritis & Rheumatism created Aug 08, 2012 | popularity not rated yet | comments 0

Clinical trial for rabies monoclonal antibody

A pivotal clinical trial for an anti-rabies human monoclonal antibody (RMAb) being developed through a collaborative partnership between MassBiologics of the University of Massachusetts Medical School and the Serum Institute ...

Diseases, Conditions, Syndromes created Aug 07, 2012 | popularity not rated yet | comments 0

Adalimumab is a promising therapy for children with Crohn's disease

Adalimumab (an anti-tumor necrosis factor [TNF] antibody) is effective in maintaining remission in certain pediatric patients with Crohn's disease, according to a new study in Gastroenterology, the official journal of the ...

Diseases, Conditions, Syndromes created Aug 06, 2012 | popularity not rated yet | comments 0