Scientists develop drug that slows Alzheimer's in mice
A drug developed by scientists at the Salk Institute for Biological Studies, known as J147, reverses memory deficits and slows Alzheimer's disease in aged mice following short-term treatment. The findings, ...
Alzheimer's disease & dementia
May 13, 2013 |
4.2 / 5 (5) |
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Researchers describe how breast cancer cells acquire drug resistance
A seven-year quest to understand how breast cancer cells resist treatment with the targeted therapy lapatinib has revealed a previously unknown molecular network that regulates cell death. The discovery provides new avenues ...
Cancer
May 07, 2013 |
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Study identifies genes, pathways altered during relaxation response practice
A new study from investigators at the Benson-Henry Institute for Mind/Body Medicine at Massachusetts General Hospital (MGH) and Beth Israel Deaconess Medical Center (BIDMC) finds that elicitation of the relaxation response ...
Psychology & Psychiatry
May 01, 2013 |
5 / 5 (1) |
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PTSD research: Distinct gene activity patterns from childhood abuse
Abuse during childhood is different. A study of adult civilians with PTSD (post-traumatic stress disorder) has shown that individuals with a history of childhood abuse have distinct, profound changes in gene activity patterns, ...
Psychology & Psychiatry
May 01, 2013 |
4 / 5 (4) |
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Key mechanism for a common form of Alzheimer's disease discovered
Scientists from the Icahn School of Medicine at Mount Sinai, in collaboration with researchers from Icelandic Heart Association, Sage Bionetworks, and other institutions, have discovered that a network of genes involved in ...
Alzheimer's disease & dementia
Apr 25, 2013 |
4.6 / 5 (5) |
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Researchers discover link between inherited endocrine tumor syndrome and well-studied cell pathway
(Medical Xpress)—A mutation in a protein called menin causes a hereditary cancer syndrome called MEN1 (multiple endocrine neoplasia type 1). Individuals with MEN1 are at a substantially increased risk of ...
Cancer
Apr 24, 2013 |
4 / 5 (1) |
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Deficiency in p53 anti-tumor protein delays DNA repair after radiation
Researchers at Moffitt Cancer Center have found that a deficiency in an important anti-tumor protein, p53, can slow or delay DNA repair after radiation treatment. They suggest that this is because p53 regulates the expression ...
Cancer
Apr 23, 2013 |
4 / 5 (1) |
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Large-scale genetic study defines relationship between primary sclerosing cholangitis and other autoimmune diseases
For the first time, scientists show that a leading cause of liver transplant, primary sclerosing cholangitis (PSC), is a distinct disease from inflammatory bowel disease, opening up new avenues for specific PSC treatments.
Genetics
Apr 21, 2013 |
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Hundreds of alterations and potential drug targets to starve cancer tumors identified
A massive study analyzing gene expression data from 22 tumor types has identified multiple metabolic expression changes associated with cancer. The analysis, conducted by researchers at Columbia University Medical Center, ...
Cancer
Apr 21, 2013 |
5 / 5 (4) |
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Key pathway to stop dangerous, out-of-control inflammation discovered
A potential new strategy to developing new drugs to control inflammation without serious side effects has been found by Georgia State University researchers and international colleagues.
Inflammatory disorders
Apr 09, 2013 |
5 / 5 (4) |
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Feeling hungry may protect the brain against Alzheimer's disease, study finds
The feeling of hunger itself may protect against Alzheimer's disease, according to study published today in the journal PLOS ONE. Interestingly, the results of this study in mice suggest that mild hunger ...
Alzheimer's disease & dementia
Apr 03, 2013 |
5 / 5 (6) |
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The metabolic weathervane of cancer
Highly expressed in various cancers and known for its cytoprotective properties, TRAP1 protein has been identified as a potential target for antitumor treatments. As a result of the research conducted by Len Neckers, from ...
Cancer
Apr 01, 2013 |
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Scientists tie dietary influences to changes in gene expression and physiology
Sometimes you just can't resist a tiny piece of chocolate cake. Even the most health-conscious eaters find themselves indulging in junk foods from time to time. New research by scientists at the University of Massachusetts ...
Medical research
Mar 28, 2013 |
5 / 5 (2) |
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When timing is everything: Research says beneficial mutations need specific circumstances to win out
When it comes to the sort of beneficial mutations that drive natural selection, there's new evidence that, evolutionarily speaking, timing is everything.
Genetics
Mar 20, 2013 |
5 / 5 (1) |
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International consortium builds 'Google Map' of human metabolism
Building on earlier pioneering work by researchers at the University of California, San Diego, an international consortium of university researchers has produced the most comprehensive virtual reconstruction ...
Medical research
Mar 03, 2013 |
3.8 / 5 (5) |
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