Pediatrics

Efficacy of DTaP, tdap holds despite pertactin deficiency

(HealthDay)—Despite an increased proportion of Bordetella pertussis isolates lacking pertactin, vaccine effectiveness (VE) is still high in Vermont for the five-dose diphtheria, tetanus, and acellular pertussis vaccine ...

Diseases, Conditions, Syndromes

New discovery may lead the way to improved whooping cough vaccine

Scientists at Trinity College Dublin have made novel discoveries concerning the current vaccine against whooping cough that may lead to the development of an improved future vaccine. The findings could help reduce the incidence ...

Diseases, Conditions, Syndromes

Cases of whooping cough in US highest in decades

Pertussis is at its highest level nationally in a half-century. But cases of pertussis, also known as whooping cough, often decline in late fall into early winter.

Diseases, Conditions, Syndromes

5 Questions: Yvonne Maldonado on whooping cough

(Medical Xpress)—The United States is on track to have its biggest whooping cough epidemic in 60 years, with more than 21,000 cases already reported in 2012. The highly contagious and potentially fatal disease, officially ...

Diseases, Conditions, Syndromes

Bordetella parapertussis outbreak in southeastern Minnesota in 2014

Study reports that an outbreak of Bordetella parapertussis occurred in 2014 in Southeastern Minnesota, in the months of October through December. This research is presented at ASM's 55th Interscience Conference of Antimicrobial ...

Immunology

Whooping cough vaccine antigen disappearing from bacteria in US

Vaccines for whooping cough contain three to five protective antigens, the presence of which are critical to the vaccine's effectiveness. But one of the antigens, pertactin, which had been present in almost all isolates of ...

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