Diseases, Conditions, Syndromes

Whooping cough on the rise again

(Medical Xpress)—Whooping cough (Pertussis) is a highly contagious disease caused by the bacterium Bordetella pertussis and characterized by attacks of severe coughing, often (but not always) with a characteristic high-pitched ...

Diseases, Conditions, Syndromes

Whooping cough bacterium evolves in Australia

The bacterium that causes whooping cough, Bordetella pertussis, has changed in Australia - most likely in response to the vaccine used to prevent the disease - with a possible reduced effectiveness of the vaccine as a result, ...

Medications

Whooping cough evolving to beat antibiotics and possibly vaccine

A new strain of Bordetella pertussis – the bacterium that causes whooping cough – has become resistant to antibiotic treatment and may also be resistant to the vaccine used in China. A UNSW Sydney academic says the growing ...

Diseases, Conditions, Syndromes

Whooping cough vaccine: The power of first impressions

The current whooping cough vaccine was universally adopted in the US in 1996 to replace the original vaccine based on killed Bordetella pertussis because of a stronger safety profile. The new formulation was found to be effective ...

Pediatrics

Why is whooping cough on the rise?

Watching an infant suffer through a bout of whooping cough is agonizing. Blue face scrunched with effort, the baby strains to take a breath through a narrowed windpipe. She struggles, choking, for what seems like eons. Finally, ...

Pediatrics

Efficacy of DTaP, tdap holds despite pertactin deficiency

(HealthDay)—Despite an increased proportion of Bordetella pertussis isolates lacking pertactin, vaccine effectiveness (VE) is still high in Vermont for the five-dose diphtheria, tetanus, and acellular pertussis vaccine ...

Immunology

Whooping cough vaccine antigen disappearing from bacteria in US

Vaccines for whooping cough contain three to five protective antigens, the presence of which are critical to the vaccine's effectiveness. But one of the antigens, pertactin, which had been present in almost all isolates of ...

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