RANK protein promotes the initiation, progression and metastasis of human breast cancer
Researchers from the Bellvitge Biomedical Research Institute (IDIBELL) have shown that overactivation of the RANK signalling pathway promotes the initiation, progression and metastasis of tumours in human breast epithelial ...
Cancer
Apr 24, 2012 |
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New signaling pathway linked to breast cancer metastasis
Lymph nodes help to fight off infections by producing immune cells and filtering foreign materials from the body, such as bacteria or cancer cells. Thus, one of the first places that cancer cells are found when they leave ...
Cancer
Apr 02, 2012 |
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Researchers identify mechanism that makes breast cancer invasive
A new study has identified a key mechanism that causes breast cancer to spread. The research, published by Cell Press on March 30th in the journal Molecular Cell, enhances our knowledge about the signals that drive cancer ...
Cancer
Mar 29, 2012 |
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Cancer paradigm shift: Biomarker links clinical outcome with new model of lethal tumor metabolism
Researchers at the Kimmel Cancer Center at Jefferson have demonstrated for the first time that the metabolic biomarker MCT4 directly links clinical outcomes with a new model of tumor metabolism that has patients "feeding" ...
Cancer
Mar 15, 2012 |
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Inhibiting cell migration in breast cancer
(Medical Xpress) -- Scientists from the Friedrich Miescher Institute for Biomedical Research together with colleagues from the University of Fribourg have discovered a signaling mechanism controlling mobility ...
Cancer
Mar 14, 2012 |
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Protein that functions in normal breast may also contribute to breast cancer metastasis
The trefoil factor 3 (TFF3) protein protects and maintains the integrity of the epithelial surface in the normal breast. New research has found that while TFF3 protein expression is higher in well-differentiated low grade ...
Cancer
Feb 16, 2012 |
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Metastatic breast cancer hitches a free ride from the immune system
Inflammatory breast cancer (IBC) is the most lethal form of breast cancer . It spreads easily through the lymphatic and blood vessels, forming metastasis which can lead to multi-organ failure. New research published in BioMed ...
Immunology
Feb 10, 2012 |
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How early breast tumors become deadly: A small group of molecules might hold the answer
Researchers have discovered a restricted pattern of molecules that differentiate early-stage breast tumors from invasive, life-threatening cancer. They also found a similar molecular signature that correlated with the aggressiveness ...
Cancer
Feb 07, 2012 |
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Agent shows ability to suppress brain metastasis and related damage
(Medical Xpress) -- Scientists are one step closer to repairing the damage caused by brain metastasis, a major challenge in cancer treatment, according to data published in Cancer Research, a journal of the American Associ ...
Cancer
Jan 03, 2012 |
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UK researchers present findings from Kentucky breast cancer patients with disease relapse
The University of Kentucky Markey Cancer Center breast oncologist Dr. Suleiman Massarweh and his research team presented findings from their studies on relapse of breast cancer at the San Antonio Breast Cancer Symposium this ...
Cancer
Dec 23, 2011 |
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Researchers show molecule inhibits metastasis of colon, melanoma cancers
Researchers at the Medical College of Wisconsin have shown that a protein can inhibit metastasis of colon and melanoma cancers. The findings are published in the October 10, 2011 issue of Proceedings of the National Academy of ...
Cancer
Oct 10, 2011 |
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New potential therapeutic target for breast cancer
A possible new target for breast cancer therapy comes from the discovery that the Tyk2 protein helps suppress the growth and metastasis of breast tumors, as reported in Journal of Interferon & Cytokine Re ...
Cancer
Oct 05, 2011 |
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Cell movement provides clues to aggressive breast cancer
Researchers from the University of Michigan Comprehensive Cancer Center have identified a specific molecule that alters how breast cancer cells move. This affects the cells' ability to spread or metastasize to distant parts ...
Cancer
Oct 03, 2011 |
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New insights into links between stress and cancer
(Medical Xpress) -- Trinity College Dublin researchers have discovered that blocking a particular stress response can significantly reduce the metastasis (or spread) of breast cancer.
Cancer
Jun 01, 2011 |
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Researchers discover protein that could help prevent the spread of cancer
A protein capable of halting the spread of breast cancer cells could lead to a therapy for preventing or limiting the spread of the disease.
Cancer
May 04, 2011 |
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