Arthritis & Rheumatism

How mitochondrial damage ignites the 'auto-inflammatory fire'

Mitochondria are self-contained organelles (they possess their own mini-chromosome and DNA) residing within cells and are charged with the job of generating the chemical energy needed to fuel functions essential to life and ...

Medical research

Preventing calcification of bioprosthetic heart valves

A defective heart valve is the second most common form of heart disease. Most cases involve a narrowed aortic valve, but often the mitral valve can also be affected. Prostheses significantly increase the life expectancy of ...

Medical research

Research challenges decades-old understanding of how we hear sound

Researchers at Linköping University, Sweden, have made several discoveries on the functioning mechanisms of the inner hair cells of the ear, which convert sounds into nerve signals that are processed in the brain. The results, ...

Immunology

The immune system: Knocked off balance

Instead of protecting us, the immune system can sometimes go awry, as in the case of autoimmune diseases and allergies. A Ludwig-Maximilian-Universitaet (LMU) in Munich team has dissected how mast cells regulate their calcium ...

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