Oncology & Cancer

TB vaccine shrinks liver cancer tumors in mice

A UC Davis Health study found that a single dose of Bacillus Calmette-Guérin (BCG), the vaccine for tuberculosis (TB), reduced liver tumor burden and extended the survival of mice with liver cancer. The study, published ...

Oncology & Cancer

Researchers reveal mechanism of drug reactivating tumor suppressors

Researchers have revealed the mechanism of a drug shown to be effective in treating certain types of cancer, which targets a protein modification silencing the expression of multiple tumor suppressor genes. They also demonstrated ...

Oncology & Cancer

Liver metastasis, metabolism, and a therapeutic conundrum

A new study led by researchers at the Herbert Irving Comprehensive Cancer Center (HICCC) has identified a crucial factor that can drive tumor cells to spread to the liver. The work, which is published in the current issue ...

Oncology & Cancer

What reactivates dormant cancer cells?

Researchers at Columbia University have found a molecule that is responsible for arousing dormant cells from breast cancer and nudging them to create metastases. Silencing this molecule, called Malat1, in mice with breast ...

Oncology & Cancer

Hitchhiking cancer vaccine makes progress in the clinic

Therapeutic cancer vaccines are an appealing strategy for treating malignancies. In theory, when a patient is injected with peptide antigens—protein fragments from mutant proteins only expressed by tumor cells—T cells ...

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