Repeats of DNA sequences, often referred to as "junk DNA" or "dark matter," that are found in chromosomes and could contribute to cancer or other diseases have been challenging to identify and characterize.
Mar 13, 2024
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Targeting two brain tumor-associated proteins—rather than one—with CAR T cell therapy shows promise as a strategy for reducing solid tumor growth in patients with recurrent glioblastoma (GBM), an aggressive form of brain ...
Mar 13, 2024
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A molecule has demonstrated its ability to kill tumor cells and incite an immune response in preclinical models of small cell lung cancer (SCLC), according to UT Southwestern Medical Center researchers. The findings, published ...
Mar 12, 2024
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Some cancerous tumors hijack proteins that act as "brakes" on our immune system and use them to form a sort of shield against immune recognition. Immunotherapy treatments have been created that turn off these "brakes" and ...
Mar 11, 2024
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A pioneering Phase I CAR T cell therapy trial for the treatment of glioblastoma at City of Hope demonstrates promising clinical activity against incurable brain tumors, according to research published in Nature Medicine.
Mar 7, 2024
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UC San Francisco researchers have designed a candidate drug that could help make pancreatic cancer, which is almost always fatal, a treatable, perhaps even curable, condition.
Mar 5, 2024
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Chimeric antigen receptor (CAR)-T cell therapy is a potent emerging weapon against cancer, altering patients' T cells so they can better find and destroy tumor cells. But CAR-T cell therapy doesn't work well in every cancer—including ...
Mar 1, 2024
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Researchers at the University of Michigan Health Rogel Cancer Center are exploiting a unique biological feature of glioblastoma to gain a better understanding of how this puzzling brain cancer develops and how to target new ...
Feb 29, 2024
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Researchers at the University of Colorado Anschutz Medical Campus studying interactions between nerves and tumor microenvironments have found that commonly used drugs like botox may stop or slow the progression of certain ...
Feb 28, 2024
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One of the immune system's primary roles is to detect and kill cells that have acquired cancerous mutations. However, some early-stage cancer cells manage to evade this surveillance and develop into more advanced tumors.
Feb 28, 2024
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