Alzheimer's disease & dementia

Alzheimer's discovery reveals dire effect of toxic tau protein

Alzheimer's disease researchers at the University of Virginia have discovered how harmful tau proteins damage the essential operating instructions for our brain cells, a finding that could lead to new treatments.

Genetics

Acetaldehyde dehydrogenases in liver zonation and liver cancer

A study, published in the journal Gene Expression and led by Brady Jin-Smith from the Department of Pathology at Tulane University, focuses on ALDHs, a group of key enzymes that catalyze the irreversible oxidation of various ...

Diseases, Conditions, Syndromes

Scientists find a 'scarcode' common across damaged organs

Scarring goes more than skin deep. It can occur in any organ because of injury from smoking and excessive alcohol consumption or as a byproduct of chronic conditions like endometriosis, cardiovascular disease and autoimmune ...

Oncology & Cancer

Study identifies strategy to avoid resistance to cancer therapy

Resistance to therapies is one of the obstacles to overcome in cancer treatments. Understanding the mechanisms of this resistance is essential to design strategies that favor tumor cell death. A study led by the Protein Kinases ...

Neuroscience

Demystifying a mammal's brain, cell by cell

A group of scientists, including several at Harvard, have dived deeper into the mammalian brain than ever before by categorizing and mapping at the molecular level all of its thousands of different cell types.

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