Potential new colorectal cancer treatment target identified
(HealthDay)—The cell surface marker carcinoembryonic antigen-related cell adhesion molecule 6 (CD66c) is a novel marker for colorectal cancer stem cell isolation, which halts tumor growth when silenced, ...
Cancer
Oct 07, 2012 |
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Study sheds light on bone marrow stem cell therapy for pancreatic recovery
Researchers at Cedars-Sinai's Maxine Dunitz Neurosurgical Institute have found that a blood vessel-building gene boosts the ability of human bone marrow stem cells to sustain pancreatic recovery in a laboratory mouse model ...
Medical research
Oct 02, 2012 |
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Cortex development depends on a protein
As outlined in a study published in Developmental Cell, researchers have discovered a novel function for p27 in the control of interneuron migration in the developing cerebral cortex.
Medical research
Oct 02, 2012 |
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A form of small pox virus shows potential for treating triple-negative breast cancer
Researchers from Memorial Sloan-Kettering Cancer Center (MSKCC) in New York City have shown that a new vaccinia virus, acting as both an oncolytic and anti-angiogenic agent, can enter and kill triple-negative breast cancer ...
Cancer
Oct 01, 2012 |
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Physiological role of a novel hormone FNDC5/irisin revealed in humans
A research team led by Dr. Christos Mantzoros, MD, PhD, at Beth Israel Deaconess Medical Center, Harvard Medical School, has published new findings elucidating the molecular and clinical role of FNDC5/irisin in humans.
Medical research
Oct 01, 2012 |
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An old drug finds a new use
Dr. Anglea Wandinger-Ness and Dr. Laurie Hudson were awarded a Provocative Questions grant to investigate the use of R-ketorolac against ovarian cancer. Ketorolac is an NSAID that the FDA approved for human use in 1991. They ...
Medications
Sep 27, 2012 |
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Researchers solve key part of old mystery in generating muscle mass
Working with mice, Johns Hopkins researchers have solved a key part of a muscle regeneration mystery plaguing scientists for years, adding strong support to the theory that muscle mass can be built without ...
Medical research
Sep 27, 2012 |
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Major cancer protein amplifies global gene expression
Scientists may have discovered why a protein called MYC can provoke a variety of cancers. Like many proteins associated with cancer, MYC helps regulate cell growth. A study carried out by researchers at the National Institutes ...
Genetics
Sep 27, 2012 |
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New way to weed out problem stem cells, making therapy safer
Mayo Clinic researchers have found a way to detect and eliminate potentially troublemaking stem cells to make stem cell therapy safer. Induced Pluripotent Stem cells, also known as iPS cells, are bioengineered from adult ...
Medical research
Sep 27, 2012 |
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Surgeons use woman's own tissue to rebuild ear lost to cancer
(Medical Xpress)—In a series of a half-dozen operations spanning 20 months, surgeons at Johns Hopkins have successfully reconstructed the entire ear and part of the skull of a 42-year-old woman from Bel ...
Surgery
Sep 27, 2012 |
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Researchers develop blood test that accurately detects early stages of lung, breast cancer in humans
Researchers at Kansas State University have developed a simple blood test that can accurately detect the beginning stages of cancer.
Cancer
Sep 26, 2012 |
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Self-regulating networks dictate the genetic program of tumor cells
Scientists at Charité – Universitätsmedizin Berlin could explain a yet unknown regulatory network that controls the growth of tumor cells. Understanding such networks is an important task in molecular tumor biology in ...
Cancer
Sep 25, 2012 |
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Obesity promotes prostate cancer by altering gene regulation
Prostate cancer is one of the most common cancers in men and early treatment is usually very successful. However, like other cancers, obesity increases the risk of aggressive prostate disease. New research, published in BioMed ...
Cancer
Sep 24, 2012 |
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Scientists reverse Alzheimer's-like memory loss in animal models by blocking EGFR signaling
A team of neuroscientists and chemists from the U.S. and China today publish research suggesting that a class of currently used anti-cancer drugs as well as several previously untested synthetic compounds show effectiveness ...
Alzheimer's disease & dementia
Sep 24, 2012 |
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Denosumab reduces burden of giant-cell tumor of the bone
Treatment with denosumab, a drug targeted against a protein that helps promote bone destruction, decreased the number of tumor giant cells in patients with giant-cell tumor of the bone, and increased new bone formation, according ...
Cancer
Sep 21, 2012 |
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