Mutations in the KRAS gene are the major driver of pancreatic cancer. The resulting protein controls multiple signaling pathways involved in cell growth and survival. In cancer, the gene is mutated to be permanently "on," ...
Jun 29, 2023
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A team at DTU Health Tech, led by Associate Professor Alireza Dolatshahi-Pirouz, has made a leap forward in tissue regeneration by creating a multi-leveled scaffold that encompasses properties of native bone on both the nano, ...
Jun 27, 2023
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Northwestern Medicine scientists have identified a novel vulnerability in a subset of genes commonly mutated in cancer, according to a study recently published in the Journal of Clinical Investigation.
Jun 26, 2023
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Scientists led by Sabine Taschner-Mandl, Ph.D., St. Anna Children's Cancer Research Institute, and Nikolaus Fortelny, Ph.D., Paris Lodron University of Salzburg, are the first to analyze bone marrow metastases from childhood ...
Jun 26, 2023
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Immunology research led by Harvard Medical School has taken a closer look at the role of B-cells in fighting cancer. In a paper, "B-cell-specific checkpoint molecules that regulate anti-tumor immunity," published in Nature, ...
Heart failure is a common condition, though it currently lacks a cure. And treatments can only manage symptoms, often with side effects. But recent research published in ACS Biomaterials Science & Engineering could open up ...
Jun 20, 2023
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Researchers from The University of Texas MD Anderson Cancer Center found the KRAS G12C inhibitor adagrasib showed promising activity suppressing cancer growth not only within the lungs but also in brain metastases for patients ...
Jun 16, 2023
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Chromatin states and their associated epigenetic information play a crucial role in maintaining the identity of cells as they divide. Histone post-translational modifications (PTMs) are important determinants of the cellular ...
Jun 16, 2023
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15 years ago, a woman in her thirties was diagnosed with metastatic kidney cancer. The oncologist José Pablo Maroto, from the Hospital de la Santa Creu i Sant Pau, in Barcelona, decided to treat her with the drug temsirolimus, ...
Jun 14, 2023
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Lung mesenchymal cells, which are critical components of the lung's unique structure, also play important roles in disease and recovery from injury, yet knowledge is limited about their biology or how they initiate diseases ...
Jun 13, 2023
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