Researchers study use of dasatinib for patients with high-risk MDS
Researchers at Moffitt Cancer Center have completed a phase II clinical trial to determine the safety and efficacy of dasatinib for patients with higher-risk myelodysplastic syndromes (MDS), chronic myelomonocytic leukemia, ...
Cancer
Mar 21, 2013 |
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Platelet-rich plasma significantly improves outcomes in patients with tennis elbow
Platelet rich plasma (PRP) therapy has been used to manage pain associated with torn tendons, muscles and ligaments, mostly in athletes, at all levels. Though it has anecdotally been successful, the evidence to support its ...
Surgery
Mar 21, 2013 |
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Comparing combination therapies for advanced head and neck cancer shows no improvement
Locally advanced squamous cell carcinoma of the head and neck is a potentially curable disease in nearly every patient at the time of diagnosis, yet despite the most aggressive efforts, up to 30-50 percent ...
Cancer
Mar 07, 2013 |
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New drug combination could prevent head and neck cancer in high-risk patients
(Medical Xpress)—A new drug combination shows promise in reducing the risk for patients with advanced oral precancerous lesions to develop squamous cell carcinoma of the head and neck. The results of the study, which included ...
Cancer
Feb 19, 2013 |
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Novel designed molecules could stop colon cancer metastasis
A Basque research consortium has managed to stop the development of colon cancer and its liver metastasis in an experimental model using mice. This breakthrough, which could open new avenues for the future treatment of these ...
Cancer
Feb 14, 2013 |
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Stem cell source an important factor, impacting ability to treat myocardial infarction
When a research team from Denmark and Sweden compared the therapeutic capabilities of adipose-derived stem cells (ASCs) versus bone marrow-derived stem cells (BMSCs) obtained from a single 84 year-old male donor with ischemic ...
Medical research
Feb 13, 2013 |
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Protein that represses critical checkpoint protein for cellular growth helps drive tumor development
(Medical Xpress)—One of the hallmarks of cancer is unchecked cellular growth. Fortunately, our cells contain a number of tumor suppressor proteins, including the cell cycle regulator p21, to keep cell growth ...
Cancer
Feb 13, 2013 |
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Messenger substance and signalling molecule influence the development of the skin's immune cells
A signalling molecule known as Axl has been discovered on immune cells of the epidermis. This recently published finding provides new insight into the development of important skin immune cells known as Langerhans ...
Medical research
Jan 29, 2013 |
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Researchers identify enzyme involved in deadly brain tumors
One of the most common types of brain tumors in adults, glioblastoma multiforme, is one of the most devastating. Even with recent advances in surgery, radiation and chemotherapy, the aggressive and invasive tumors become ...
Cancer
Jan 17, 2013 |
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Nobel scientist Rita Levi-Montalcini dies in Rome
Rita Levi-Montalcini, a biologist who conducted underground research in defiance of Fascist persecution and went on to win a Nobel Prize for helping unlock the mysteries of the cell, died at her home in Rome ...
Other
Dec 30, 2012 |
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Changes in progenitor cell population in breast may be overlooked factor in breast cancer
The DNA mutations that accumulate over time as women age are not the sole contributor to the higher frequency of breast cancer in women over 50, Mark LaBarge, PhD, a researcher at Lawrence Berkeley National Laboratory (LBNL) ...
Cancer
Dec 17, 2012 |
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PR+ cells add prognostic value in luminal A breast cancer
(HealthDay)—Semiquantitative immunohistochemical expression of progesterone receptor-positive tumor cells improves prediction of survival within luminal A breast cancers, according to a study published ...
Cancer
Dec 17, 2012 |
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Breast cancer drug could hold the key to fighting other tumours
New research out of the United Kingdom is showing that a common drug used in the fight against breast cancer could also be employed in the fight against other tumours. The drug in question is geldanamycin, ...
Cancer
Dec 05, 2012 |
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Improving chemotherapy effectiveness by acting on the immune system
An Inserm team in Dijon directed by François Ghiringhelli is to publish an article this week in the Nature Medicine review. The article suggests that two chemotherapy drugs frequently used to treat digestive and breast cancers ...
Immunology
Dec 04, 2012 |
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Stem cell-derived dopaminergic neurons rescue motor defects in Parkinsonian monkeys
Parkinson's disease is a degenerative disorder of the central nervous system that is characterized by tremors, rigidity, slowness of movement, and difficulty walking. It is caused by loss of the neurons that produce the neurotransmitter ...
Parkinson's & Movement disorders
Dec 03, 2012 |
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