Oncology & Cancer

Enzyme checkpoint identified in tumor-associated macrophages

A study by a scientific team from the University of Vienna and the MedUni Vienna, recently published in Cellular & Molecular Immunology, shows that the enzyme phosphoglycerate dehydrogenase (PHGDH) acts as a metabolic checkpoint ...

Oncology & Cancer

Re-exposing a cancer protein to enhance immunotherapy

Successful immunotherapy for cancer involves activating a person's own T cells to identify telltale proteins called antigens on the surface of a tumor and attack it. But some tumors have a trick: They hide themselves from ...

Oncology & Cancer

How one type of lung cancer can transform into another

Lung tumors called adenocarcinomas sometimes respond to initially effective treatments by transforming into a much more aggressive small cell lung cancer (SCLC) that spreads rapidly and has few options for treatment. Researchers ...

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