Genetic mutations in early development have been implicated in several psychiatric disorders such as autism and schizophrenia, symptoms of which typically manifest during childhood and early adulthood. However, mutations ...
Jul 29, 2022
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82
A team of researchers affiliated with several institutions in the U.S. and the U.K. has found a link between the APOBEC3A enzyme and the most prevalent mutational signatures in cancer cell lines. In their paper published ...
Bat cells have specific molecular barriers to deal with SARS-CoV-2 replication, according to a study published in Journal of Virology which includes the participation of Jordi Serra-Cobo, lecturer of the Faculty of Biology ...
Jul 26, 2022
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42
One of the greatest challenges facing cancer researchers is to understand why some patients don't respond to treatments. In some cases, tumors exhibit what is known as multidrug resistance (MDR), which significantly limits ...
Jul 22, 2022
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152
Worldwide, breast cancer (BC) is the second most common cancer. Pharmacologically targeting cyclin-dependent kinase 4 and 6 (CDK4 & 6) has proven to be a successful therapeutic approach in patients with estrogen receptor-positive ...
Jul 6, 2022
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6
Hepatitis E virus (HEV) is widespread, and so far there is no effective drug to treat it. In the search for one, the so-called rocaglates have come into focus: plant compounds that can inhibit the replication of viruses. ...
Jun 27, 2022
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3
A machine-learning model has helped scientists discover hundreds of genetic mutations in cancer that are undetectable by current genome sequencing, according to a study published in the journal Science Advances.
Jun 16, 2022
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Researchers at The University of Texas MD Anderson Cancer Center have developed a new approach to quantify tumor-specific total mRNA levels from patient tumor samples, which contain both cancer and non-cancer cells. Using ...
Jun 13, 2022
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28
Researchers at Massachusetts General Hospital (MGH) have discovered that the interferon gamma receptor (IFNgR) signaling pathway is critical for susceptibility of glioblastoma tumors to killing by CAR T-cell immunotherapy. ...
Jun 10, 2022
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52
A team of researchers from the College of Design and Engineering, the N.1 Institute for Health and the Cancer Science Institute of Singapore at the National University of Singapore has recently engineered in vitro tumor models ...
Jun 2, 2022
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