Oncology & Cancer

Overall survival up for melanoma brain metastases

(HealthDay)—Overall survival (OS) for patients with melanoma brain metastases (MBM) has improved significantly since 2000, according to a study published online Oct. 12 in Cancer.

Oncology & Cancer

Checkpoint inhibitors no less safe with radiation

(HealthDay)—Immune-related adverse events (IRAEs), including pneumonitis, are not more common in patients with metastatic lung cancer who receive both immune checkpoint inhibitors (CPIs) and thoracic radiotherapy (TRT), ...

Oncology & Cancer

Immune checkpoint inhibitor endocrine dysfunction explored

(HealthDay)—Patients receiving immune checkpoint inhibitor (ICI) regimens may experience endocrine dysfunction, with increased risk of thyroid dysfunction and hypophysitis for patients on combination therapy, according ...

Oncology & Cancer

Alternative splicing, an important mechanism for cancer

Cancer, which is one of the leading causes of death worldwide, arises from the disruption of essential mechanisms of the normal cell life cycle, such as replication control, DNA repair and cell death. Thanks to the advances ...

Oncology & Cancer

Chronic cell death promotes liver cancer

Liver cancer occurs predominantly in patients whose liver has been damaged as a result of chronic disease. Until now, it was not known how these events are linked at the molecular level. An international team of scientists ...

Diseases, Conditions, Syndromes

Trigger for fatty liver in obesity found

Morbid obesity affects the liver: Almost one-third of all adults suffer from chronic fatty liver disease, which can lead to infections and even trigger cancer. Researchers at the University Children's Hospital Zurich and ...

Immunology

New insights into why the immune system fails to see cancer

Cancer hides in plain sight of the immune system. The body's natural tumor surveillance programs should be able to detect and attack rogue cancer cells when they arise, and yet when cancer thrives, it does so because these ...

Oncology & Cancer

Combining immunotherapies effective against mouse model of cancer

Rhabdomyosarcoma, a cancer made up of cells that normally develop into skeletal muscles, is the most common soft tissue cancer in children. If it is detected early and localized in certain areas, rhabdomyosarcoma is usually ...

Medical research

The link between protein aggregation and aging

Not only does our way of life determine how long we live but so too does our genetic material. Of particular importance here is a genetic program that is controlled by the insulin receptor. A team of researchers from the ...

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