Insight into the dazzling impact of insulin in cells
Australian scientists have charted the path of insulin action in cells in precise detail like never before. This provides a comprehensive blueprint for understanding what goes wrong in diabetes.
Medical research
May 21, 2013 |
4.6 / 5 (8) |
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Scientists identify molecular trigger for Alzheimer's disease
Researchers have pinpointed a catalytic trigger for the onset of Alzheimer's disease – when the fundamental structure of a protein molecule changes to cause a chain reaction that leads to the death of neurons ...
Alzheimer's disease & dementia
May 20, 2013 |
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Making a window for drug delivery in the blood-brain barrier
(Medical Xpress)—The blood-brain barrier (BBB) prevents most large or hydrophilic (polar) molecules from getting into the brain. For many neurological diseases, like Parkinson's, the presence of the BBB ...
Medical research
Apr 30, 2013 |
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Mapping of cancer cell fuel pumps paves the way for new drugs
For the first time, researchers at Karolinska Institutet in Sweden have managed to obtain detailed images of the way in which the transport protein GLUT transports sugars into cells. Since tumours are highly dependent on ...
Cancer
Apr 28, 2013 |
4.7 / 5 (3) |
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Fusion and cell death in the development of skeletal muscle
(Medical Xpress)—Membrane fusion is a highly regulated event, both inside cells, and between them. From the moment a sperm first fuses with an egg, subsequent developmental events depend upon its proper ...
Medical research
Apr 26, 2013 |
4.3 / 5 (3) |
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Drug reverses Alzheimer's disease deficits in mice, research confirms
An anti-cancer drug reverses memory deficits in an Alzheimer's disease mouse model, University of Pittsburgh Graduate School of Public Health researchers confirm in the journal Science.
Alzheimer's disease & dementia
22 hours ago |
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Antibiotics: A new understanding of sulfonamide nervous system side effects
Since the discovery of Prontosil in 1932, sulfonamide antibiotics have been used to combat a wide spectrum of bacterial infections, from acne to chlamydia and pneumonia. However, their side effects can include serious neurological ...
Medical research
22 hours ago |
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Finding a family for a pair of orphan receptors in the brain
Researchers at Emory University have identified a protein that stimulates a pair of "orphan receptors" found in the brain, solving a long-standing biological puzzle and possibly leading to future treatments for neurological ...
Medical research
May 21, 2013 |
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Anti-CD47 antibody may offer new route to successful cancer vaccination
(Medical Xpress)—Scientists at the School of Medicine have shown that their previously identified therapeutic approach to fight cancer via immune cells called macrophages also prompts the disease-fighting killer T cells ...
Cancer
May 21, 2013 |
4.5 / 5 (2) |
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Research uncovers a potential role of two proteins in diabetes
(Medical Xpress)—Flinders University researchers are breaking new ground in a decade-long journey to pinpoint the function of two closely related proteins.
Diabetes
May 20, 2013 |
5 / 5 (2) |
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Insight into cell survival
Researchers at Tokyo Institute of Technology report details on the biological mechanisms through which cells degrade own cellular material, allowing them to survive starvation conditions.
Medical research
May 17, 2013 |
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Promising treatment for progeria within reach
Pharmaceuticals that inhibit a specific enzyme may be useful in treating progeria, or accelerated aging in children. A new study performed at the Sahlgrenska Academy indicates that the development of progeria ...
Diseases, Conditions, Syndromes
May 16, 2013 |
5 / 5 (4) |
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Vicious cycle: Obesity sustained by changes in brain biochemistry
With obesity reaching epidemic levels in some parts of the world, scientists have only begun to understand why it is such a persistent condition. A study in the Journal of Biological Chemistry adds substantially to the st ...
Medical research
May 16, 2013 |
3 / 5 (2) |
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Study of the machinery of cells reveals clues to neurological disorder
(Medical Xpress)—Investigation by researchers from the University of Exeter and ETH Zurich has shed new light on a protein which is linked to a common neurological disorder called Charcot-Marie-Tooth disease.
Neuroscience
May 16, 2013 |
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Same musicians: Brand new tune
A small ensemble of musicians can produce an infinite number of melodies, harmonies and rhythms. So too, do a handful of workhorse signaling pathways that interact to construct multiple structures that comprise ...
Medical research
May 14, 2013 |
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