Immunology

Study identifies key player in T cell 'education'

Vanderbilt researchers have identified a protein that is key to the "education" of immature T cells in the thymus. The findings, reported in the Journal of Experimental Medicine, could inform therapeutic strategies for enhancing ...

Neuroscience

Revealing roles of dementia proteins in normal memory

New research has revealed how the tau protein, a critical element in the formation of Alzheimer's disease, is also involved in normal learning processes in the healthy brain—potentially providing a focal point for future ...

Oncology & Cancer

Potential new treatment for angioimmunoblastic T-cell lymphoma

A type of blood cell cancer called angioimmunoblastic T-cell lymphoma (AITL) can develop as mutations accumulate with age in the stem cells from which the T cells in the blood develop. However, the underlying mechanism by ...

Medications

FDA approves first targeted therapy for HER2-low breast cancer

The U.S. Food and Drug Administration has approved Enhertu (am-trastuzumab-deruxtecan-nxki), an intravenous infusion treatment for patients with unresectable or metastatic human epidermal growth factor receptor 2 (HER2)-low ...

Oncology & Cancer

Early, encouraging data for glioblastoma treatment reported at ASCO

All of the newly diagnosed glioblastoma multiforme patients enrolled in a Phase 1 clinical trial at the University of Alabama at Birmingham have exceeded both their median and expected progression-free survivals. Two patients, ...

Neuroscience

Scientists uncover key factor in neocortex development

Scientists at the Texas A&M University College of Medicine have made a breakthrough discovery about the development of the brain. This new information contributes to our understanding of how the part of the brain that makes ...

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