News tagged with cellular pathways
Sensory hair cells regenerated, hearing restored in mammal ear
Hearing loss is a significant public health problem affecting close to 50 million people in the United States alone. Sensorineural hearing loss is the most common form and is caused by the loss of sensory ...
Neuroscience
Jan 09, 2013 |
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Scientists find mechanism that triggers immune responses to DNA
(Medical Xpress)—Free-floating pieces of DNA in a cell's watery interior can mean bad things: invading viruses, bacteria, or parasites, ruptured cellular membranes, or disease. Genetic material is meant to be contained ...
Medical research
Dec 21, 2012 |
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Hundreds of alterations and potential drug targets to starve cancer tumors identified
A massive study analyzing gene expression data from 22 tumor types has identified multiple metabolic expression changes associated with cancer. The analysis, conducted by researchers at Columbia University Medical Center, ...
Cancer
Apr 21, 2013 |
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How mitochondrial DNA defects cause inherited deafness
(Medical Xpress) -- Yale scientists have discovered the molecular pathway by which maternally inherited deafness appears to occur: Mitochondrial DNA mutations trigger a signaling cascade, resulting in programmed ...
Medical research
Feb 17, 2012 |
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Study shines light on how stress circuits learn
Researchers at the University of Calgary's Hotchkiss Brain Institute have discovered that stress circuits in the brain undergo profound learning early in life. Using a number of cutting edge approaches, including ...
Neuroscience
Apr 07, 2013 |
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Researchers identify key genes and prototype predictive test for schizophrenia
An Indiana University-led research team, along with a group of national and international collaborators, has identified and prioritized a comprehensive group of genes most associated with schizophrenia that together can generate ...
Genetics
May 15, 2012 |
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Researchers discover key to immune cell's 'internal guidance' system
University of British Columbia researchers have discovered the molecular pathway that enables receptors inside immune cells to find, and flag, fragments of pathogens trying to invade a host.
Immunology
Feb 05, 2012 |
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Discovery shows medications can treat inflammation without increasing risk for infection
In a discovery that can fundamentally change how drugs for arthritis, and potentially many other diseases, are made, University of Utah medical researchers have identified a way to treat inflammation while potentially minimizing ...
Inflammatory disorders
Nov 11, 2012 |
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Using rabies virus, researcher tracks inputs to dopamine neurons
A genetically-modified version of the rabies virus is helping scientists at Harvard to trace neural pathways in the brain, a research effort that could one day lead to treatments for Parkinson's disease and addiction.
Neuroscience
Jun 06, 2012 |
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Researchers identify brain pathway triggering impulsive eating
New research from the University of Georgia has identified the neural pathways in an insect brain tied to eating for pleasure, a discovery that sheds light on mirror impulsive eating pathways in the human ...
Medical research
Feb 28, 2013 |
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Trapping malaria parasites inside host cell basis for new drugs
One of the most insidious ways that parasitic diseases such as malaria and toxoplasmosis wreak their havoc is by hijacking their host's natural cellular processes, turning self against self. Researchers from ...
Medical research
Jan 16, 2013 |
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Researchers use genomics to identify a molecular-based treatment for a viral skin cancer
Four years after they discovered the viral roots of a rare skin cancer, researchers at the University of Pittsburgh Cancer Institute (UPCI) and the School of Medicine have now identified a molecule activated by this virus ...
Cancer
May 09, 2012 |
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Discovery explains how cellular pathways converge to regulate food intake and body weight
In the complex chain of molecular events that underlie eating behaviors and body weight, the AMP-activated protein kinase (AMPK) enzyme has proven to be a critical link.
Medical research
Jul 03, 2012 |
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Using planarian flatworms to understand organ regeneration
Researchers report in the journal Developmental Cell that they have identified genes that control growth and regeneration of the intestine in the freshwater planarian Schmidtea mediterranea.
Medical research
Oct 25, 2012 |
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How major signaling pathways are wired to our genome gives new insight into disease processes
Whitehead Institute scientists have determined that master transcription factors determine the genes regulated by key signaling pathways. In this way, signaling pathways are targeted to genes that are most relevant to each ...
Medical research
Oct 27, 2011 |
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