Metabolic biomarkers can predict mortality in the ICU
A metabolic profile of intensive care unit (ICU) patients based on biomarkers of four metabolites can be used to accurately predict mortality, according to a new study.
Diseases, Conditions, Syndromes
May 20, 2013 |
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Novel mechanism allows Legionella to hide in body
(Medical Xpress)—The feared Legionella pneumophila is responsible for legionellosis, an infectious disease that can lead to pneumonia. To infect humans, this pathogen has developed a complex method that allows it to camouflage ...
Diseases, Conditions, Syndromes
May 20, 2013 |
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What role do processing bodies play in cell survival and protection against viral infection?
As scientists learn more about processing bodies (PBs), granules present within normal cells, they are unraveling the complex role PBs play in maintaining cellular homeostasis by regulating RNA metabolism ...
Medical research
May 16, 2013 |
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Malaria parasite protein identified as potential new target for drug treatment
Scientists have discovered how a protein within the malaria parasite is essential to its survival as it develops inside a mosquito. They believe their findings identify this protein as a potential new target for drug treatments ...
Medical research
Apr 25, 2013 |
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Uncleaned cells mean weak muscles
The protein complex mTORC1 promotes muscle growth. However, should this complex remain constantly active, it impairs the ability of the cells to self-clean, causing myopathy. Scientists working with Markus ...
Medical research
Apr 23, 2013 |
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Genetic alterations linked with bladder cancer risk, recurrence, progression, and patient survival
A new analysis has found that genetic alterations in a particular cellular pathway are linked with bladder cancer risk, recurrence, disease progression, and patient survival. Published early online in Cancer, a peer- review ...
Cancer
Mar 25, 2013 |
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Protein in fat cells that stimulates inflammatory signaling helps put gears in motion for onset of diet-induced obesity
Poor diet and lifestyle choices set the stage for obesity and diabetes, but the immune system plays a relatively underappreciated role in accelerating this process. Metabolic changes in fat cells stimulate ...
Medical research
Mar 15, 2013 |
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Shining red mice help Czechs fight bowel cancer, skin disease
Injected with a fluorescent protein to make them glow bright red, laboratory mice are helping Czech scientists better understand the causes behind intestinal cancers and skin diseases while leaving the rodents unscathed.
Medical research
Mar 13, 2013 |
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Scientists find calcium is the initial trigger in our immune response to healing
For the first time scientists studying the cellular processes underlying the body's response to healing have revealed how a flash of calcium is the very first step in repairing damaged tissue. The findings, published in Current Bi ...
Surgery
Feb 14, 2013 |
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Life experiences put their stamp on the next generation: New insights from epigenetics
The 18th century natural philosopher Jean-Baptiste Lamarck proposed that the necks of giraffes lengthened as a consequence of the cumulative effort, across generations, to reach leaves just out of their grasp. This view of ...
Psychology & Psychiatry
Feb 14, 2013 |
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RNA promotes metastasis in lung cancer
The vast majority – approximately 80 percent – of our DNA does not code for proteins, yet it gets transcribed into RNA. These RNA molecules are called non-coding and fulfill multiple tasks in the cell. Alongside a well-studied ...
Cancer
Feb 05, 2013 |
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More than just a backup system: PI3K-Delta in tumour surveillance
If something is really important, it's best not to rely on it. This basic principle is followed equally by human engineers – for example, the NASA space shuttle has three main engines – and by nature. Thus it could ...
Cancer
Jan 30, 2013 |
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Trapping malaria parasites inside host cell basis for new drugs
One of the most insidious ways that parasitic diseases such as malaria and toxoplasmosis wreak their havoc is by hijacking their host's natural cellular processes, turning self against self. Researchers from ...
Medical research
Jan 16, 2013 |
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New study finds key mechanism in calcium regulation
All living cells keep their cellular calcium concentration at a very low level. Since a small increase in calcium can affect many critical cellular functions (an elevated calcium concentration over an extended period can ...
Neuroscience
Jan 03, 2013 |
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Cholesterol helps regulate key signaling proteins in the cell
Cholesterol plays a key role in regulating proteins involved in cell signaling and may be important to many other cell processes, an international team of researchers has found.
Medical research
Dec 19, 2012 |
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