News tagged with cellular structure
How serotonin receptors can shape drug effects, from LSD to migraine medication
New findings by researchers carrying out experiments at the U.S. Department of Energy Office of Science's Advanced Photon Source (APS) help explain why some drugs that interact with two kinds of human serotonin ...
Medical research
May 17, 2013 |
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Study identifies new approach to improving treatment for MS and other conditions
(Medical Xpress)—Working with lab mice models of multiple sclerosis (MS), UC Davis scientists have detected a novel molecular target for the design of drugs that could be safer and more effective than current FDA-approved ...
Alzheimer's disease & dementia
May 17, 2013 |
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Discovery reshapes understanding of embryonic development
(Medical Xpress)—When a baby is born, one of the first things a parent will do is count fingers and toes. New research conducted at UC San Francisco sheds lights on how these specialized digits are formed.
Medical research
May 01, 2013 |
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Scientists create molecular map to guide treatment of multiple sclerosis
A team of scientists from the Scripps Research Institute, collaborating with members of the drug discovery company Receptos, has created the first high-resolution virtual image of cellular structures called ...
Medical research
Feb 16, 2012 |
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How mitochondrial DNA defects cause inherited deafness
(Medical Xpress) -- Yale scientists have discovered the molecular pathway by which maternally inherited deafness appears to occur: Mitochondrial DNA mutations trigger a signaling cascade, resulting in programmed ...
Medical research
Feb 17, 2012 |
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Study reveals how serotonin receptors can shape drug effects from LSD to migraine medication
A team including scientists from The Scripps Research Institute (TSRI), the University of North Carolina at Chapel Hill and the Chinese Academy of Sciences has determined and analyzed the high-resolution ...
Medical research
Mar 21, 2013 |
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Discovery sheds light on Alzheimer's mystery
(Medical Xpress)—In 1906, when Alois Alzheimer discovered the neurodegenerative disease that would later be named for him, he saw amyloid-beta plaques and neurofibrillary tangles inside the brain. Several decades later, ...
Alzheimer's disease & dementia
Oct 22, 2012 |
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BRAF inhibitor treatment causes melanoma cells to shift how they produce energy
A multi-institutional study has revealed that BRAF-positive metastatic malignant melanomas develop resistance to treatment with drugs targeting the BRAF/MEK growth pathway through a major change in metabolism. The findings, ...
Cancer
Mar 08, 2013 |
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Metabolism in the brain fluctuates with circadian rhythm
(Medical Xpress)—The rhythm of life is driven by the cycles of day and night, and most organisms carry in their cells a common, (roughly) 24-hour beat. In animals, this rhythm emerges from a tiny brain ...
Neuroscience
Aug 28, 2012 |
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Circadian rhythms can be modified for potential treatment of disorders
(Medical Xpress)—UC Irvine-led studies have revealed the cellular mechanism by which circadian rhythms – also known as the body clock – modify energy metabolism and also have identified novel compounds that control ...
Cardiology
Jan 22, 2013 |
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Study identifies adhesion molecules key to cancer's spread through the body
Although tumor metastasis causes about 90 percent of cancer deaths, the exact mechanism that allows cancer cells to spread from one part of the body to another is not well understood. One key question is ...
Cancer
Oct 09, 2012 |
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Structure of a bond formed by two proteins critical for hearing and balance described for the first time
Researchers have mapped the precise 3-D atomic structure of a thin protein filament critical for cells in the inner ear and calculated the force necessary to pull it apart.
Medical research
Nov 07, 2012 |
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Study shows antidepressant could do double duty as diabetes drug
University of Texas Medical Branch at Galveston researchers have discovered that the commonly used antidepressant drug paroxetine could also become a therapy for the vascular complications of diabetes.
Diabetes
Dec 14, 2012 |
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Cancer's sweet tooth may be its weak link
Researchers at Albert Einstein College of Medicine of Yeshiva University have discovered that cancer cells tap into a natural recycling system to obtain the energy they need to keep dividing. In a study with ...
Cancer
Nov 16, 2011 |
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Structure that edits messenger RNA transcripts defective in two different forms of motor neuron diseases
Amyotrophic lateral sclerosis (ALS) and spinal muscular atrophy (SMA) are degenerative motor neuron diseases in which the key mutated genes are involved in RNA metabolism. This similarity suggests that a ...
Medical research
Apr 26, 2013 |
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