Low pH in tumours counteracts the desired effect of the drug chloroquine, according to a new study from Karolinska Institutet in Sweden. The results, which are published in the journal Autophagy, might explain possible lack ...
Feb 11, 2014
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Combining a compound from broccoli with an antimalarial drug prevents prostate cancer in mice, University of Pittsburgh Cancer Institute (UPCI) researchers discovered.
Sep 17, 2013
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Gene analysis of malaria parasites has pinpointed western Cambodia as the hotspot of strains that are dangerously resistant to artesiminin, the frontline drug against the disease, scientists said on Sunday.
Apr 28, 2013
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In the most extensive screen of its kind, Texas Biomed scientists in San Antonio have demonstrated the feasibility of repurposing already-approved drugs for use against highly pathogenic bacteria and viruses. The pathogens ...
Apr 9, 2013
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The process of autophagy cleans cells – they wrap up the bad stuff and then dispose of it. And so it stands to reason that inhibiting autophagy would make cancer cells less able to cleanse themselves of chemotherapy and ...
Apr 8, 2013
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An extract from a shrub often used for medicinal purposes in tropical Africa may have lethal effects against a dangerous parasite that transmits malaria, according to a multi-institutional team of scientists led by researchers ...
Mar 8, 2013
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A malarial drug is showing promise in stopping breast cancer before it starts, Mason researchers are discovering during a clinical trial.
Nov 1, 2012
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Malaria-drug monitoring over the past 30 years has shown that malaria parasites develop resistance to medicine, and the first signs of resistance to the newest drugs have just been observed. At the same time, resistance monitoring ...
Oct 3, 2012
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Medicines for Malaria Venture has developed a framework to evaluate the risk of resistance for the antimalarial compounds in its portfolio. A paper based on this work: A framework for assessing the risk of resistance for ...
Aug 22, 2012
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All cells have the ability to recycle unwanted or damaged proteins and reuse the building blocks as food. But cancer cells have ramped up the system, called autophagy, and rely on it to escape damage in the face of chemotherapy ...
May 8, 2012
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