News tagged with chromosomal aberrations


A new mechanism that contributes to the evolution of cancer

Cancer arises from the accumulation of mutations and structural changes in chromosomes, which in some cases give rise to combinations that favour the growth or expansion of the disease. In this context, chromosomes tend to ...

Cancer created Jan 31, 2013 | popularity 5 / 5 (1) | comments 0

Fusion gene contributes to glioblastoma progression

Fusion genes are common chromosomal aberrations in many cancers, and can be used as prognostic markers and drug targets in clinical practice.

Cancer created Jan 09, 2013 | popularity 5 / 5 (1) | comments 0

Novel test identifies patients most likely to benefit from ALK inhibition therapy

Approximately one in 20 patients with non-small cell lung carcinoma (NSCLC) has chromosomal aberrations targeting the anaplastic lymphoma kinase (ALK) gene. This has considerable implications for treatment because these patients ...

Medical research created Dec 12, 2012 | popularity not rated yet | comments 0 | with audio podcast

Baby's genome deciphered prenatally from parents' lab tests

Scientists have successfully sequenced the genome of a baby in the womb without tapping its protective fluid sac. This non-invasive approach to obtaining the fetal genome is reported in the June 6 issue of ...

Genetics created Jun 06, 2012 | popularity 5 / 5 (6) | comments 0 | with audio podcast

Children exposed to the common pollutant naphthalene show signs of chromosomal damage

According to a new study, children exposed to high levels of the common air pollutant naphthalene are at increased risk for chromosomal aberrations (CAs), which have been previously associated with cancer. These include chromosomal ...

Health created May 29, 2012 | popularity not rated yet | comments 0 | with audio podcast

Intratumor heterogeneity seen in renal carcinomas

(HealthDay) -- Extensive intratumor heterogeneity, seen in samples obtained from renal carcinomas, may lead to underestimation of the tumor genomics based on single tumor-biopsy samples, according to a study ...

Cancer created Mar 08, 2012 | popularity not rated yet | comments 0

Patterns of chromosome abnormality: The key to cancer?

A healthy genome is characterized by 23 pairs of chromosomes, and even a small change in this structure — such as an extra copy of a single chromosome — can lead to severe physical impairment. So it's no surprise ...

Cancer created Jan 23, 2012 | popularity not rated yet | comments 0