News tagged with chromosomal aberrations
A new mechanism that contributes to the evolution of cancer
Cancer arises from the accumulation of mutations and structural changes in chromosomes, which in some cases give rise to combinations that favour the growth or expansion of the disease. In this context, chromosomes tend to ...
Cancer
Jan 31, 2013 |
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Fusion gene contributes to glioblastoma progression
Fusion genes are common chromosomal aberrations in many cancers, and can be used as prognostic markers and drug targets in clinical practice.
Cancer
Jan 09, 2013 |
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Novel test identifies patients most likely to benefit from ALK inhibition therapy
Approximately one in 20 patients with non-small cell lung carcinoma (NSCLC) has chromosomal aberrations targeting the anaplastic lymphoma kinase (ALK) gene. This has considerable implications for treatment because these patients ...
Medical research
Dec 12, 2012 |
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Baby's genome deciphered prenatally from parents' lab tests
Scientists have successfully sequenced the genome of a baby in the womb without tapping its protective fluid sac. This non-invasive approach to obtaining the fetal genome is reported in the June 6 issue of ...
Genetics
Jun 06, 2012 |
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Children exposed to the common pollutant naphthalene show signs of chromosomal damage
According to a new study, children exposed to high levels of the common air pollutant naphthalene are at increased risk for chromosomal aberrations (CAs), which have been previously associated with cancer. These include chromosomal ...
Health
May 29, 2012 |
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Intratumor heterogeneity seen in renal carcinomas
(HealthDay) -- Extensive intratumor heterogeneity, seen in samples obtained from renal carcinomas, may lead to underestimation of the tumor genomics based on single tumor-biopsy samples, according to a study ...
Cancer
Mar 08, 2012 |
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Patterns of chromosome abnormality: The key to cancer?
A healthy genome is characterized by 23 pairs of chromosomes, and even a small change in this structure such as an extra copy of a single chromosome can lead to severe physical impairment. So it's no surprise ...
Cancer
Jan 23, 2012 |
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