News tagged with clinical sciences

Muscle health depends on sugar superstructure

For many inherited diseases, such as cystic fibrosis or Huntington disease, the disease-causing genetic mutation damages or removes a protein that has an essential role in the body. This protein defect is the root cause of ...

Aug 08, 2013
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Targeting pancreatic cancer drug resistance

Pancreatic cancer is one of the most deadly and intractable forms of cancer, with a 5-year survival rate of only 6%. Novel therapies are urgently needed, as conventional and targeted approaches have not been successful and ...

Jul 08, 2013
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Hijacking stress response in cancer

(Medical Xpress)—Cancer cells have alteration in metabolic pathways as a result of oncogenes that promote tumor growth. NRF2 (nuclear factor erythroid-derived 2-related factor 2) works as a "master gene" that turns on stress ...

Jul 02, 2013
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Empowering children in clinical trials

There is evidence that over 50 percent of medicinal products developed for children have not been tested or authorised for use by this age group. The research project RESPECT ('Relating Expectations and Needs to Participation ...

Jun 20, 2013
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