News tagged with cytosine

Cytosine

Cytosine (C) is one of the four main bases found in DNA and RNA, along with adenine, guanine, and thymine (uracil in RNA). It is a pyrimidine derivative, with a heterocyclic aromatic ring and two substituents attached (an amine group at position 4 and a keto group at position 2). The nucleoside of cytosine is cytidine. In Watson-Crick base pairing, it forms three hydrogen bonds with guanine.

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Mapping the embryonic epigenome

A large, multi-institutional research team involved in the NIH Epigenome Roadmap Project has published a sweeping analysis in the current issue of the journal Cell of how genes are turned on and off to direct early human ...

Genetics May 09, 2013 | 5 / 5 (3) | 0 |

Epigenetic marker 5hmC opens door to studying its role in developmental disorders and disease

Nearly every cell in the human body carries a copy of the full human genome. So how is it that the cells that detect light in the human eye are so different from those of, say, the beating heart or the spleen?

Genetics Feb 04, 2013 | 5 / 5 (1) | 0 |

Search for epigenetic decoder leads scientists to Rett Syndrome

(Medical Xpress)—A few years ago, scientists discovered an unexpected layer of information woven into the genetic code – a nucleotide called 5-hydroxymethylcytosine, or 5hmC. Its meaning was unknown at the time, but a ...

Medical research Dec 21, 2012 | 5 / 5 (1) | 5 |

New technique could transform epigenetics research

(Medical Xpress) -- Collaboration between scientists at Cambridge University and the Babraham Institute have demonstrated a new technique that will significantly improve scientists' ability to perform epigenetics ...

Genetics Apr 26, 2012 | 5 / 5 (2) | 1 |

Patterns of new DNA letter in brain suggest distinct function

In 2009, the DNA alphabet expanded. Scientists discovered that an extra letter or "sixth nucleotide" was surprisingly abundant in DNA from stem cells and brain cells.

Neuroscience Oct 30, 2011 | 5 / 5 (8) | 0 |

Hopkins team discovers how DNA changes

Using human kidney cells and brain tissue from adult mice, Johns Hopkins scientists have uncovered the sequence of steps that makes normally stable DNA undergo the crucial chemical changes implicated in cancers, psychiatric ...

Medical research Apr 14, 2011 | 5 / 5 (1) | 0 |