Oncology & Cancer

AI analysis of cancer mutations may improve therapy

Cancer has many faces—no wonder, then, that the range of cancer-causing mutations is huge as well. The totality of such genomic alterations in an individual is what experts call a "mutational landscape." These landscapes ...

Immunology

Anti-viral rapid reaction force

After host cells have been attacked by a virus, they present parts of the pathogen on their surface. Thanks to these virus components, the killer cells patrolling in the body (CD8+ T lymphocytes) can recognise the infected ...

Genetics

Skin cells reveal DNA's genetic mosaic

(Medical Xpress)—The prevailing wisdom has been that every cell in the body contains identical DNA. However, a new study of stem cells derived from the skin has found that genetic variations are widespread in the body's ...

Oncology & Cancer

Origin of chromosomal oddity in some cancer cells identified

Surveys of the genomic terrain of cancer have turned up a curious phenomenon in some tumor cells: a massive rearrangement of DNA in one or a few chromosomes, thought to be produced during a single cell cycle. In a new study, ...

Medical research

Study helps explain varying outcomes for cancer, Down Syndrome

Aneuploidy is a condition in which cells contain an abnormal number of chromosomes, and is known to be the cause of many types of cancer and genetic disorders, including Down Syndrome. The condition is also the leading cause ...

Medical research

Unraveling tumor growth one stem cell at a time

Researchers at the University of Cambridge have discovered that a single mutation in a leukemia-associated gene reduces the ability of blood stem cells to make more blood stem cells, but leaves their progeny daughter cells ...

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