The process that allows our brains to learn and generate new memories also leads to degeneration as we age, according to a new study by researchers at MIT.
Jun 4, 2015
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Researchers in the UC Department of Cancer Biology have found new protein players that help keep genome stability—a promising finding with the potential to help with the development of new targeted therapeutics in diseases ...
Mar 10, 2015
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UT Southwestern Medical Center researchers have demonstrated in both cancer cell lines and in mice that blocking critical DNA repair mechanisms could improve the effectiveness of radiation therapy for highly fatal brain tumors ...
Apr 8, 2014
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By detailing a process required for repairing DNA breakage, scientists at the Duke Cancer Institute have gained a better understanding of how cells deal with the barrage of damage that can contribute to cancer and other diseases.
Sep 30, 2013
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Women carrying a mutation in the BRCA1- or BRCA2- genes (which control the suppression of breast and ovarian cancer) who have undergone diagnostic radiation to the chest before the age of 30 are more likely to develop breast ...
Sep 6, 2012
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AZD1390, an ataxia telangiectasia mutant (ATM) kinase inhibitor, demonstrated a manageable safety profile in both recurrent and newly diagnosed glioblastoma (GBM) patients when given in combination with standard-of-care radiotherapy ...
Apr 9, 2024
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A novel cellular pathway regulates DNA damage and structural changes in cardiomyocytes, which contributes to the development of cardiac hypertrophy, according to a Northwestern Medicine study published in Circulation.
Oct 12, 2023
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Scientists have discovered that the cells of early human embryos are often unable to repair damage to their DNA. The researchers say that this has important implications for the proposed use of gene editing techniques to ...
Jun 26, 2023
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In the tough war against glioblastoma, scientists are taking a cue from viruses on how to make the aggressive cancer more vulnerable to treatment.
Nov 1, 2022
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A cancer-specific L-type amino acid transporter 1 (LAT1) is highly expressed in cancer tissues. Inhibiting the function of LAT1 has been known to have anti-tumor effects, but there has been limited progress in the development ...
Jan 4, 2021
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