News tagged with dna damage
Related topics: cancer cells , cells , dna repair , breast cancer , cancer
Ten new diabetes gene links offer picture of biology underlying disease
(Medical Xpress) -- Ten more DNA regions linked to type 2 diabetes have been discovered by an international team of researchers, bringing the total to over 60.
Genetics
Aug 12, 2012 |
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Study shows gene defect's role in autism-like behavior
Scientists affiliated with the UC Davis MIND Institute have discovered how a defective gene causes brain changes that lead to the atypical social behavior characteristic of autism. The research offers a potential target for ...
Autism spectrum disorders
Aug 10, 2012 |
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Researchers discover gene that permanently stops cancer cell proliferation
Researchers at Case Western Reserve University School of Medicine have discovered a mutant form of the gene, Chk1, that when expressed in cancer cells, permanently stopped their proliferation and caused cell death without ...
Cancer
Aug 01, 2012 |
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DNA damage in roofers due to PAH exposure -- possible cancer link
Roofers and road construction workers who use hot asphalt are exposed to high levels of polycyclic aromatic hydrocarbons (PAHs). A University of Colorado Cancer Center study published this week in the British Medical Journal Op ...
Cancer
Jul 26, 2012 |
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New findings break tanning misconceptions: 'There is no such thing as a safe tan'
A new study conducted by GW School of Medicine and Health Sciences (SMHS) researchers Edward C. De Fabo, Ph.D., Frances P. Noonan, Ph.D., and Anastas Popratiloff, M.D., Ph.D., has been published in the journal Nature Communications. Their ...
Cancer
Jul 23, 2012 |
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Scientists discover an epigenetic cause of osteoarthritis
In what could be a breakthrough in the practical application of epigenetic science, U.K. scientists used human tissue samples to discover that those with osteoarthritis have a signature epigenetic change (DNA methylation) ...
Genetics
Jul 06, 2012 |
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Step closer to understanding childhood degenerative brain disease
(Medical Xpress) -- Researchers at the Australian Institute for Bioengineering and Nanotechnology (AIBN) are a step closer to understanding and combating the degenerative brain disease ataxia-telangiectasia.
Medical research
Jul 03, 2012 |
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Detector of DNA damage: Structure of a repair factor revealed
Double-stranded breaks in cellular DNA can trigger tumorigenesis. Researchers from Ludwig-Maximilians-Universitaet (LMU) in Munich, Germany, have determined the structure of a protein involved in the repair and signaling ...
Medical research
Jun 19, 2012 |
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Researchers capture major chemotherapeutic target in complex with DNA damage
A new study published in Science May 11 is shedding light on the molecular details of PARP-1, a DNA damage-detecting enzyme that when inhibited has been shown to be effective in fighting cancer and other ...
Medical research
May 10, 2012 |
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Resistant starch may offer potential to help protect against bowel cancer
Consumption of resistant starch leads to positive changes in the bowel and could protect against genetic damage implicated in bowel cancer.
Cancer
Apr 26, 2012 |
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Protein prevents DNA damage in the developing brain and might serve as a tumor suppressor
St. Jude Children's Research Hospital scientists have rewritten the job description of the protein TopBP1 after demonstrating that it guards early brain cells from DNA damage. Such damage might foreshadow later problems, ...
Neuroscience
Apr 23, 2012 |
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Scientists reprogram cancer cells with low doses of epigenetic drugs
Experimenting with cells in culture, researchers at the Johns Hopkins Kimmel Cancer Center have breathed possible new life into two drugs once considered too toxic for human cancer treatment. The drugs, azacitidine (AZA) ...
Cancer
Mar 22, 2012 |
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DNA marker predicts platinum drug response in breast, ovarian cancer
Scientists from Brigham and Women's Hospital and Dana-Farber Cancer Institute and their colleagues have found a genetic marker that predicts which aggressive "triple negative" breast cancers and certain ovarian cancers will ...
Cancer
Mar 22, 2012 |
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'Obscurins' in breast tissue may help physicians predict and detect breast cancer
A new discovery published online in The FASEB Journal may lead to a new tool to help physicians assess breast cancer risk as well as diagnose the disease. In the report, researchers from Johns Hopkins University and the Un ...
Cancer
Mar 21, 2012 |
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New study unravels mystery of a DNA repair process
(Medical Xpress) -- Scientists at the University of Sussex have uncovered the mechanism of a key process in DNA repair that helps prevent neurodegenerative diseases such as ataxia.
Medical research
Mar 14, 2012 |
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