A new study suggests a dual mechanism of actions of overactive and cytosolic re-localized BRCA1, the major guardian of genomic stability, in neurons death by aberrant DNA damage response and presenilin 1 dysfunction in Alzheimer's ...
Feb 7, 2018
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E-cigarettes are in the news again. This time with headlines that they may cause cancer.
Jan 31, 2018
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About 1 in 750 babies born in the United States has some kind of craniofacial malformation, accounting for about one-third of all birth defects.
Jan 25, 2018
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Researchers have shown for the first time how children can inherit a severe - potentially fatal - mitochondrial disease from a healthy mother. The study, led by researchers from the MRC Mitochondrial Biology Unit at the University ...
Jan 15, 2018
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University of Alberta researchers have discovered a mechanism that may make cancer cells more susceptible to treatment. The research team found that the protein RYBP prevents DNA repair in cancer cells, including breast cancer.
Jan 9, 2018
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Scientists have shown how alcohol damages DNA in stem cells, helping to explain why drinking increases your risk of cancer, according to research part-funded by Cancer Research UK and published in Nature today.
Jan 3, 2018
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Neuroblastoma (NB) is the most common solid tumor found in children. It starts in some very early forms of nerve cells found in the embryo or fetus. Amplification of the gene MYCN is a well-characterized genetic alteration ...
Dec 29, 2017
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Biophysicists have shown that following low-dose exposure to X-rays (at 80 milligrays), stem cells remain healthy, proliferate, and do not accumulate DNA damage to be passed on to their progeny. The paper was published in ...
Dec 20, 2017
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Researchers at The Wistar Institute have found that combining PARP inhibitors, recently approved for the treatment of BRCA-mutant ovarian cancer, with another small molecule inhibitor was effective to treat ovarian cancers ...
Dec 19, 2017
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When you catch a nasty cold, curling up in bed to sleep may be the only activity you can manage. Sleeping in response to stress isn't a uniquely human behavior: many other animals have the same reaction, and it's not clear ...
Dec 15, 2017
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