Telomerase is a reverse transcriptase that uses an RNA template to synthesize telomeres. These repeat sequences bind special proteins that fold the ends of chromosomes back onto themselves to create a stable cap. When this ...
Most living organisms – animals, plants, fungi, and even some types of bacteria – have an internal clock, a circadian clock that orchestrates the biochemical, physiological and behavioral functions in each cell according ...
May 10, 2018
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We all have tiny, protein-operated clocks inside our cells that operate based upon the 24-hour day cycle. These circadian clocks are important for the proper biological function of different organs - heart, liver, lungs, ...
May 7, 2018
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Researchers from the Novo Nordisk Foundation Center for Protein Research at the Faculty of Health and Medical Sciences have characterised a new protein that is important to the genetic stability of cells. It may be significant ...
May 4, 2018
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Scientists at King's College London are encouraging parents and carers to ensure even more rigorous protection of children against the harmful effects of the sun. The comments follow a study which has suggested that children ...
Apr 24, 2018
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Many chemotherapeutics act by damaging the DNA. Since cancer cells divide more often than most normal cells, they are more sensitive to DNA-damaging agents. One exception are oocytes. To prevent birth defects, they initiate ...
Apr 18, 2018
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Researchers from the Novo Nordisk Foundation Center for Protein Research have uncovered a new protein shield that aids in repairing damaged DNA in cells and affects resistance to drugs used for breast cancer treatment. The ...
Apr 16, 2018
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An international team of researchers found how cancer cells respond to DNA damage signaling when in low oxygen, or hypoxia. Through comprehensive gene expression analyses, the team determined how one family of genes controls ...
Mar 20, 2018
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Being obese or having a higher body mass index (BMI) while carrying a BRCA (BReast CAncer gene) mutation is positively linked with higher levels of damage to the DNA in normal breast gland cells, new research suggests. The ...
Mar 18, 2018
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Mitochondria are cellular organelles with their own DNA. Their role in power generation makes them susceptible to oxidative damage, including the formation of DNA-damaging chemical complexes called adducts.
Feb 23, 2018
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