News tagged with dna sequences

Related topics: genes , genome , proceedings of the national academy of sciences , chromosomes , gene expression

Breakthrough in understanding immune response

(Medical Xpress)—A team of researchers led by Professor Mark Lindsay from our Department of Pharmacy & Pharmacology has made a breakthrough in identifying the genes that regulate the immune response.

Jun 23, 2014
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Faster DNA sleuthing saves critically ill boy

A 14-year-old boy's turnaround and quick recovery after mysteriously being stricken by brain-inflaming encephalitis—which led to him being hospitalized for six weeks and put into a medically induced coma after falling critically ...

Jun 04, 2014
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A new syndrome caused by mutations in AHDC1

A team of researchers led by Baylor College of Medicine have identified the gene underlying a newly recognized genetic syndrome that has symptoms of sleep apnea, delayed speech and hyptonia, or generalized upper body weakness.

May 01, 2014
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Personalized medicine has finally arrived—or has it?

As the price for decoding a person's DNA keeps dropping, expectations for personalized medicine based on specific genetic profiling rise. But translating an individual's genetic data into finely tailored medical treatments ...

Feb 26, 2014
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Important discovery for the diagnosis of genetic diseases

A study conducted by Marie Kmita's team at the IRCM, in collaboration with Josée Dostie at McGill University, shows the importance of the chromatin architecture in controlling the activity of genes, especially those required ...

Jan 16, 2014
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DNA sequence

A DNA sequence or genetic sequence is a succession of letters representing the primary structure of a real or hypothetical DNA molecule or strand, with the capacity to carry information as described by the central dogma of molecular biology.

The possible letters are A, C, G, and T, representing the four nucleotide bases of a DNA strand — adenine, cytosine, guanine, thymine — covalently linked to a phosphodiester backbone. In the typical case, the sequences are printed abutting one another without gaps, as in the sequence AAAGTCTGAC, read left to right in the 5' to 3' direction. Short sequences of nucleotides are referred to as oligonucleotides and are used in a range of laboratory applications in molecular biology. With regard to biological function, a DNA sequence may be considered sense or antisense, and either coding or noncoding. DNA sequences can also contain "junk DNA."

Sequences can be derived from the biological raw material through a process called DNA sequencing.

In some special cases, letters besides A, T, C, and G are present in a sequence. These letters represent ambiguity. Of all the molecules sampled, there is more than one kind of nucleotide at that position. The rules of the International Union of Pure and Applied Chemistry (IUPAC) are as follows:

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