A "humanized" mouse model equipped with the immune system of a patient who needs an organ transplant beats current measures for identifying the best potential living donor, scientists report.
Aug 27, 2021
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A cohort study found that class I HLA evolutionary divergence (HED) of the donor predicts acute or chronic rejection of a liver transplant. This prognostic marker can be found rapidly at no additional cost and has the potential ...
Aug 24, 2021
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Hematopoietic stem cells—the precursors to blood cells—have been notoriously difficult to grow in a dish, a critical tool in basic research. Scientists at University of California San Diego School of Medicine have identified ...
Aug 12, 2021
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Immune cells called natural killer cells contribute to organ rejection after transplantation because they miss "self" proteins on donor cells, according to a study appearing in an upcoming issue of JASN. A better understanding ...
Jul 22, 2021
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Bone marrow transplants are procedures that infuse healthy blood stem cells into your body to replace damaged or diseased bone marrow. Just like people in need of solid organ transplants, such as hearts or kidneys, people ...
Jul 12, 2021
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Leukemia is a group of blood cancers that affects thousands of people worldwide. However, with advances in medicine, several different types of leukemia can be effectively treated with donor stem cells through allogenic stem ...
Jun 24, 2021
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A study released today in Stem Cells Translational Medicine offers hope for those suffering from a chronic, difficult to treat condition called non-tuberculous mycobacteria (NTM) lung infection. The study describes how researchers ...
May 4, 2021
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A paper by a multidisciplinary team of scientists affiliated with various Brazilian institutions, including the University of São Paulo (USP) and the National Cancer Institute (INCA), shows that people of African descent ...
Feb 2, 2021
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Clonal hematopoiesis (CH) is a recently identified condition in which mutations associated with blood cancers are detected in the blood of some healthy, usually older, individuals who don't have cancer. People with CH, while ...
Dec 5, 2020
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Blood stem cell transplants are an important part of treatment for a variety of serious conditions. However, adverse reactions of the host to donor cells present a significant risk. Now, researchers from the University of ...
Oct 27, 2020
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