News tagged with drug development
Bed sharing with parents increases risk of cot death fivefold
Bed sharing with parents is linked to a fivefold increased risk of sudden infant death syndrome (SIDS), even when the parents are non-smokers and the mother has not been drinking alcohol and does not use illegal drugs, according ...
Health
May 20, 2013 |
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Study IDs key protein for cell death, offers way to kill cancer cells by forcing them into programmed-death pathway
When cells suffer too much DNA damage, they are usually forced to undergo programmed cell death, or apoptosis. However, cancer cells often ignore these signals, flourishing even after chemotherapy drugs have ...
Genetics
May 14, 2013 |
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Scientists show how nerve wiring self-destructs
Many medical issues affect nerves, from injuries in car accidents and side effects of chemotherapy to glaucoma and multiple sclerosis. The common theme in these scenarios is destruction of nerve axons, the ...
Neuroscience
May 09, 2013 |
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Researchers uncover new target for cancer research
In a new paper released today in Nature, BioFrontiers Institute scientists at the University of Colorado Boulder, Tom Cech and Leslie Leinwand, detailed a new target for anti-cancer drug development that is sitting at the ...
Cancer
Oct 24, 2012 |
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Ethics experts call for more thoughtful optimization of drug development process
(Medical Xpress)—McGill University post-doctoral fellow Spencer Phillips Hey and Prof. Jonathan Kimmelman, Biomedical Ethics, Social Studies of Medicine, Faculty of Medicine argue that some clinical trials of new drugs ...
Medications
May 09, 2013 |
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Intractable seizures halted with experimental treatment for rare pediatric 'Pretzel syndrome'
With a better understanding of underlying mechanisms that cause a rare neurodevelopmental disorder in the Old Order Mennonite population, referred to as Pretzel syndrome, a new study reports that five children were successfully ...
Neuroscience
Apr 24, 2013 |
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Study finds child abuse can lead to stunted brain development
(Medical Xpress) -- A small team of researchers has found that various forms of child abuse can lead to stunted development in certain regions of the brain. The research carried out by Martin Teicher, Carl ...
Neuroscience
Feb 14, 2012 |
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New chemo drug gentler on fertility, tougher on cancer
A new gentler chemotherapy drug in the form of nanoparticles has been designed by Northwestern Medicine® scientists to be less toxic to a young woman's fertility but extra tough on cancer. This is the first cancer drug tested ...
Cancer
Mar 22, 2013 |
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Compound stimulates tumor-fighting protein in cancer therapy
A compound that stimulates the production of a tumor-fighting protein may improve the usefulness of the protein in cancer therapy, according to a team of researchers.
Cancer
Feb 06, 2013 |
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Blocking telomerase kills cancer cells but provokes resistance, progression
Inhibiting telomerase, an enzyme that rescues malignant cells from destruction by extending the protective caps on the ends of chromosomes, kills tumor cells but also triggers resistance pathways that allow cancer to survive ...
Cancer
Feb 21, 2012 |
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Some breast cancer spread may be triggered by a protein, study shows
Cancers rarely are deadly unless they evolve the ability to grow beyond the tissues in which they first arise. Normally, cells -- even early-stage tumor cells -- are tethered to scaffolding that helps to restrain ...
Cancer
Jan 17, 2012 |
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Drug shows some benefit for kids with autism
(HealthDay)—An experimental drug for autism did not improve levels of lethargy and social withdrawal in children who took it, but it did show some other benefits, a new study finds.
Autism spectrum disorders
May 02, 2013 |
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Long-term ADHD drug use appears safe, brain development not affected
Drugs used to treat Attention Deficit Hyperactivity Disorder (ADHD) do not appear to have long-term effects on the brain, according to new animal research from Wake Forest Baptist Medical Center.
Autism spectrum disorders
Jul 18, 2012 |
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Researchers look at the spread of dysentery from Europe to industrializing countries
Researchers have found that a bacterium that emerged centuries ago in Europe has now been spreading globally into countries undergoing rapid development and industrialization. Unlike other diarrheal diseases, this one is ...
Genetics
Aug 05, 2012 |
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Researchers link new molecular culprit to breast cancer progression
(Phys.org)—Johns Hopkins researchers have uncovered a protein "partner" commonly used by breast cancer cells to unlock genes needed for spreading the disease around the body. A report on the discovery, published November ...
Cancer
Nov 25, 2012 |
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