Heroin vaccine blocks relapse in preclinical study
Scientists at The Scripps Research Institute (TSRI) have reported successful preclinical tests of a new vaccine against heroin. The vaccine targets heroin and its psychoactive breakdown products in the bloodstream, preventing ...
Medical research
May 06, 2013 |
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Making a window for drug delivery in the blood-brain barrier
(Medical Xpress)—The blood-brain barrier (BBB) prevents most large or hydrophilic (polar) molecules from getting into the brain. For many neurological diseases, like Parkinson's, the presence of the BBB ...
Medical research
Apr 30, 2013 |
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Signature of circulating breast tumor cells that spread to the brain found
Some breast tumor circulating cells in the bloodstream are marked by a constellation of biomarkers that identify them as those destined to seed the brain with a deadly spread of cancer, said researchers led by those at Baylor ...
Cancer
Apr 10, 2013 |
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Key pathway to stop dangerous, out-of-control inflammation discovered
A potential new strategy to developing new drugs to control inflammation without serious side effects has been found by Georgia State University researchers and international colleagues.
Inflammatory disorders
Apr 09, 2013 |
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Will cell therapy become a 'third pillar' of medicine?
Treating patients with cells may one day become as common as it is now to treat the sick with drugs made from engineered proteins, antibodies or smaller chemicals, according to UC San Francisco researchers. They outlined ...
Medical research
Apr 03, 2013 |
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New discovery could lead to powerful new anti-malaria drugs
An international study has discovered a molecule which could form the basis of powerful new anti-malaria drugs. The paper "Quinolone-3-Diarylethers: a new class of drugs for a new era of malaria eradication" has been published ...
Medical research
Mar 20, 2013 |
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Study identifies adhesion molecules key to cancer's spread through the body
Although tumor metastasis causes about 90 percent of cancer deaths, the exact mechanism that allows cancer cells to spread from one part of the body to another is not well understood. One key question is ...
Cancer
Oct 09, 2012 |
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Discovery could help combat chronic pain in diabetics
(Medical Xpress) -- Researchers at the University of California, Davis, have discovered a class of natural compounds found within the body that may someday lead to pain relief for millions of diabetics and others suffering ...
Diabetes
Jun 26, 2012 |
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Researchers discover drug target for stimulating recovery from stroke
Investigators at the Stanford University School of Medicine have shown that removing a matched set of molecules that typically help to regulate the brain's capacity for forming and eliminating connections between nerve cells ...
Neuroscience
Mar 21, 2012 |
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New synthetic molecules treat autoimmune disease in mice
A team of Weizmann Institute scientists has turned the tables on an autoimmune disease. In such diseases, including Crohn's and rheumatoid arthritis, the immune system mistakenly attacks the body's tissues. But the scientists ...
Immunology
Dec 25, 2011 |
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Drugs without side effects: Researchers explore novel ways to classify proteins
Janelle Leuthaeuser is on the cutting edge of biophysics. A molecular genetics and genomics Ph.D. student, she is part of a nationwide effort to create a more efficient generation of protein-based drugs.
Medical research
Apr 26, 2013 |
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Video reveals cancer cells' Achilles' heel (w/ Video)
(Medical Xpress)—Scientists from the Manchester Collaborative Centre for Inflammation Research (MCCIR) have discovered why a particular cancer drug is so effective at killing cells. Their findings could ...
Cancer
Apr 24, 2013 |
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Research team uncovers shape of transmembrane protein partly responsible for antibiotic resistance
(Medical Xpress)—Researchers from the University of Tokyo have uncovered the physical layout of a transmembrane protein that the tiny organism Archaea relies on to keep toxins out of its cells. The protein, ...
Medical research
Mar 28, 2013 |
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Researchers design small molecule to disrupt cancer-causing protein
Researchers at Moffitt Cancer Center and colleagues at the University of South Florida have developed a small molecule that inhibits STAT3, a protein that causes cancer. This development could impact the treatment of several ...
Cancer
Mar 26, 2013 |
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New monoclonal antibody developed that can target proteins inside cancer cells
Researchers have discovered a unique monoclonal antibody that can effectively reach inside a cancer cell, a key goal for these important anticancer agents, since most proteins that cause cancer or are associated with cancer ...
Cancer
Mar 13, 2013 |
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