News tagged with drug resistance

Related topics: antibiotics · cancer cells · breast cancer · hiv · malaria

Mapping the routes to drug resistance in cancer

When a freeway shuts down because of an accident or construction, drivers find another road to take them where they're going. Likewise, when a targeted therapy blocks a pathway that enables tumors to grow, the cells usually ...

Apr 11, 2016
popularity1 comments 0

Plant metabolite promises more effective chemotherapy

Combining a new synthetic apigenin compound with existing anticancer drug treatments can reverse drug resistance, say researchers at The Hong Kong Polytechnic University (PolyU). The compound can also improve the absorption ...

Apr 05, 2016
popularity12 comments 0

Drug resistance

Drug resistance is the reduction in effectiveness of a drug in curing a disease or improving a patient's symptoms. When the drug is not intended to kill or inhibit a pathogen, then the term is equivalent to dosage failure or drug tolerance. More commonly, the term is used in the context of diseases caused by pathogens.

Pathogens are said to be drug-resistant when drugs meant to neutralize them have reduced effect. When an organism is resistant to more than one drug, it is said to be multidrug resistant.

Drug resistance is an example of evolution in microorganisms. Individuals that are not susceptible to the drug effects are capable of surviving drug treatment, and therefore have greater fitness than susceptible individuals. By the process of natural selection, drug resistant traits are selected for in subsequent offspring, resulting in a population that is drug resistant.

This text uses material from Wikipedia, licensed under CC BY-SA

Subscribe to rss feed