News tagged with drug targets
Whole genome sequencing of rare olfactory neuroblastoma
The Translational Genomics Research Institute (TGen) and the Virginia G. Piper Cancer Center at Scottsdale Healthcare have conducted whole genome sequencing (WGS) of a rare nasal tract cancer called olfactory neuroblastoma ...
Genetics
May 23, 2012 |
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A possible target for broad-range HPV therapeutics emerges
(Medical Xpress) -- Among viruses, human papilloma virus (HPV) stands out: with more than 180 distinct isotypes or variations catalogued to date, it presents an extremely difficult target for broad-range treatments. And while ...
Cancer
May 22, 2012 |
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New inflammation hormone link may pave way to study new drugs for Type 2 diabetes
A new link between obesity and type 2 diabetes found in mice could open the door to exploring new potential drug treatments for diabetes, University of Michigan Health System research has found.
Diabetes
May 15, 2012 |
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Early biomarker for pancreatic cancer identified
Researchers at the University of California, San Diego School of Medicine and Moores Cancer Center have identified a new biomarker and therapeutic target for pancreatic cancer, an often-fatal disease for which there is currently ...
Cancer
May 15, 2012 |
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Researchers identify potential target for anthrax drug
(Medical Xpress) -- Researchers at the University of Michigan have identified new targets for drugs that could potentially treat anthrax, the deadly infection caused by Bacillus anthracis.
Medical research
May 09, 2012 |
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Advanced pancreatic tumors depend on continued oncogene activity
Researchers at Dana-Farber Cancer Institute have shown that advanced pancreatic cancers in mice can't survive without continued expression of a mutant oncogene that "rewires" key metabolic pathways to fuel the cancer cells.
Cancer
Apr 26, 2012 |
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Scientists find new breast cancer genes, rewrite rulebook
Scientists at the BC Cancer Agency and University of British Columbia have identified new breast cancer genes that could change the way the disease is diagnosed and form the basis of next-generation treatments.
Cancer
Apr 18, 2012 |
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Metal binding important for metformin action
(HealthDay) -- The ability of metformin to bind mitochondrial copper may be essential to its mechanism of action, according to a study published online April 9 in Diabetes.
Diabetes
Apr 14, 2012 |
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Treatment hope for Duchenne muscular dystrophy
An international team led by the University of Melbourne Australia, has found that increasing a specific protein in muscles could help treat Duchenne muscular dystrophy (DMD), a severe and progressive muscle wasting disease ...
Diseases, Conditions, Syndromes
Apr 04, 2012 |
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Pancreatic cancer clinical trial results released
The feasibility of selecting treatment based on individual molecular characteristics was demonstrated in a first-of-its kind pancreatic cancer clinical trial reported today by the Translational Genomics Research Institute ...
Cancer
Apr 03, 2012 |
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'Druggable' protein complex identified as a therapeutic target in acute myeloid leukemia
Scientists at Cold Spring Harbor Laboratory have identified a candidate drug target for treating acute myeloid leukemia (AML), a white blood cell cancer that proliferates out of control in the bone marrow. The team, led by ...
Cancer
Apr 02, 2012 |
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Map of substrate-kinase interactions may lead to more effective cancer drugs
(Medical Xpress) -- Later-stage cancers thrive by finding detours around roadblocks that cancer drugs put in their path, but a Purdue University biochemist is creating maps that will help drugmakers close ...
Cancer
Mar 27, 2012 |
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Study reveals new details about a protein that enables cancer cells to start new tumors in distant sites
(Medical Xpress) -- A Loyola University Chicago Stritch School of Medicine study has revealed details of the complex molecular process involving a protein that enables cancer cells to establish tumors in distant parts of ...
Cancer
Mar 14, 2012 |
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Collaborative preclinical efficacy studies suggest a new target for drug addiction treatment
In preclinical studies, researchers at SRI International and Astraea Therapeutics have recently evaluated the role of a new drug receptor target that shows promise for the treatment of drug addiction.
Addiction
Mar 14, 2012 |
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Tranylcypromine antidepressant shows promise as cancer treatment
A retinoid called all-trans retinoic acid (ATRA), which is a vitamin A-derivative, is already used successfully to treat a rare sub-type of acute myeloid leukemia (AML), however this drug has not been effective for the more ...
Cancer
Mar 11, 2012 |
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