Autism spectrum disorders

Autism linked to egg cells' difficulty creating large proteins

New work from Carnegie's Ethan Greenblatt and Allan Spradling reveals that the genetic factors underlying fragile X syndrome, and potentially other autism-related disorders, stem from defects in the cell's ability to create ...

Genetics

Why does making new egg cells require so much cell death?

A highly detailed study of how the roundworm C. elegans forms oocytes suggests that the egg-making process leads to the formation and subsequent destruction of cells with an extra nucleus, but that some cellular materials ...

Oncology & Cancer

A major step towards individualized cancer therapy

Fuyuhiko Tamanoi of Kyoto University's Institute for Integrated Cell-Material Sciences (iCeMS) and colleagues in the U.S. succeeded in establishing a powerful and convenient model to analyse human cancer.

Obstetrics & gynaecology

Preconception zinc deficiency could spell bad news for fertility

An estimated 10 percent of couples in the U.S. struggle with infertility. While a variety of factors can make it difficult for some people to get pregnant, ovulation disorders are a leading cause of female infertility. Now, ...

Obstetrics & gynaecology

Like babies, eggs send signals when 'hungry'

In humans and other mammals, the female reproductive cells - the eggs or oocytes - need nourishment in order to grow and remain fertile. It is known that the egg gets its food from little arm-like feeding tubes (called filopodia) ...

Genetics

Keeping egg cells fresh with epigenetics

Keeping egg cells in stasis during childhood is a key part of female fertility. New research published today in Nature Structural and Molecular Biology sheds some light on the role of epigenetics in placing egg cells into ...

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