The tumor suppressor protein p53 is an attractive target for drug developers. But this path has so far proven difficult, as most p53 regulatory proteins operate via protein-protein interactions, which make for poor drug targets, ...
Jan 13, 2013
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The process researchers use to generate induced pluripotent stem cells (iPSCs)—a special type of stem cell that can be made in the lab from any type of adult cell—is time consuming and inefficient. To speed things up, ...
Sep 25, 2012
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(Medical Xpress) -- The ability to control whether certain stem cells ultimately become bone cells holds great promise for regenerative medicine and potential therapies aimed at treating metabolic bone diseases.
Jul 9, 2012
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Researchers at Winship Cancer Institute are developing a technique to remove cancer cells' defenses against radiation.
Mar 15, 2012
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Researchers at the University of Iowa have worked out the exact function of an enzyme that is critical for normal muscle structure and is involved in several muscular dystrophies. The findings, which were published Jan. 6 ...
Jan 9, 2012
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A study by scientists at the University of California, San Diego and UC Irvine has identified an enzyme called a proteasome phosphatase that appears to regulate removal of damaged proteins from a cell. The understanding of ...
Sep 27, 2011
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UC Irvine researchers have found a new approach to the creation of customized therapies for virulent flu strains that resist current antiviral drugs.
Jul 12, 2011
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A study led by an Oregon State University pharmaceutical sciences researcher has produced a proof of principle for a new "universal" means of treating COVID-19.
Oct 18, 2022
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Patients with chronic obstructive pulmonary disease (COPD) are more likely to have coronary heart disease (CHD), but no specific phenotypes have a higher risk, according to a study published online April 27 in PLOS ONE.
May 17, 2022
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Researchers at Johannes Gutenberg University Mainz (JGU) in Germany and the Institute of Molecular Biology of Barcelona in Spain have discovered how the blood plasma protein fetuin-B binds to the enzyme meprin β and used ...
Apr 20, 2021
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