An analysis of the genomes and epigenomes of lean and obese mice and humans has turned up a wealth of clues about how genes and the environment conspire to trigger diabetes, Johns Hopkins researchers say. Their findings reveal ...
Jan 6, 2015
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It is now widely understood that cancer is a disease of acquired defects in genes and gene function. An article published Feb. 9 in Science, and authored by Andrew Feinberg, M.D., of the Johns Hopkins Kimmel Cancer Center ...
Feb 10, 2023
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A pair of studies led by University of North Carolina Lineberger Comprehensive Cancer Center researchers could aid in improved diagnosis for melanoma, the deadliest form of skin cancer.
Mar 5, 2019
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Congestive heart failure is a terminal disease that affects nearly 6 million Americans. Yet its management is limited to symptomatic treatments because the causal mechanisms of congestive heart failure—including its most ...
Aug 9, 2018
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Scientists from King's College London have identified patterns of epigenetic changes involved in autism spectrum disorder (ASD) by studying genetically identical twins who differ in autism traits. The study, published in ...
Apr 23, 2013
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Gliomas can begin as benign growth in brain tissue but almost all eventually morph into malignant cancers called GBMs. Despite medical and surgical advances, GBMs remain one of the most deadly cancers in humans.
Dec 1, 2015
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A new study led by Dr. Manel Esteller, Director of the Epigenetics and Cancer Biology Program (PEBC) of Bellvitge Biomedical Research Institute (IDIBELL), ICREA researcher and Professor of Genetics at University of Barcelona ...
Aug 18, 2016
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Epigenetic changes in the islets of Langerhans of the pancreas can be detected in patients several years before the diagnosis of type 2 diabetes (T2D). These changes are responsible for the altered methylation activity of ...
Sep 10, 2020
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Tumor suppressor genes protect cells from malignant transformation. If they are turned off as a result of chemical modifications in DNA, called epigenetic labels, this contributes to the development of cancer. As opposed ...
Jun 12, 2017
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Researchers at King's College London have discovered that sensitivity to pain could be altered by a person's lifestyle and environment throughout their lifetime. The study is the first to find that pain sensitivity, previously ...
Feb 4, 2014
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