Oncology & Cancer

ASCO: Trametinib improves survival in metastatic melanoma

(HealthDay) -- For patients with metastatic melanoma with activating mutations in serine-threonine protein kinase B-RAF (BRAF), treatment with the oral selective MEK inhibitor trametinib is associated with improved progression-free ...

Diseases, Conditions, Syndromes

Risk for Guillain-Barré syndrome up after Ad.26.COV2.S vaccination

The incidence of Guillain-Barré syndrome (GBS) is increased after Ad.26.COV2.S vaccination, but incidence is not increased after mRNA vaccination, according to a study published online April 26 in JAMA Network Open.

Diabetes

Metformin linked to increased risk of acute dialysis in T2DM

(HealthDay)—For patients with type 2 diabetes, metformin is associated with about a 50 percent increase in the risk of acute dialysis compared to sulfonylureas, according to a study published online Aug. 18 in Diabetes, ...

Overweight & Obesity

Zonisamide 400 mg enhances weight loss for obese

(HealthDay)—A prescription medication originally developed to treat epilepsy may help obese adults shed weight when combined with routine nutritional counseling, researchers say.

Medications

Semaglutide superior to liraglutide for weight loss

(HealthDay)—Among adults with overweight or obesity, once-weekly subcutaneous semaglutide plus counseling for diet and physical activity results in significantly greater weight loss at 68 weeks than once-daily subcutaneous ...

Overweight & Obesity

Weight loss linked to reduced cancer incidence, mortality

(HealthDay) -- Weight loss, particularly intentional weight loss, is associated with a reduced incidence of cancer and mortality, especially for women and for obesity-related cancers, according to a review published online ...

Diabetes

CVD risk similar for metformin + insulin or sulfonylureas

(HealthDay)—For patients with type 2 diabetes, the risk of myocardial infarction (MI) or stroke is similar for treatment with insulin or sulfonylureas in combination with metformin, according to a study published online ...

Diseases, Conditions, Syndromes

Oxiplex improves outcomes after lumbar discectomy

(HealthDay) -- The use of Oxiplex gel (containing carboxymethylcellulose, polyethylene oxide, and calcium) to coat the surgical site during discectomy procedures for the treatment of lumbar disc herniation is associated with ...

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