Neuroscience

Head-mounted microscope reaches deeper into mouse brains

Researchers have developed a miniature microscope that is designed for high-resolution 3D images inside the brains of living mice. By imaging deeper into the brain than previously possible with miniature widefield microscopes, ...

Biomedical technology

New technology could make biopsies a thing of the past

A Columbia Engineering team has developed a technology that could replace conventional biopsies and histology with real-time imaging within the living body. Described in a new paper published today in Nature Biomedical Engineering, ...

Medical research

Nanobody-drug conjugates hijack the human vitamin B12 uptake route

A major challenge in cancer therapy is selectively targeting cancer cells over healthy ones. A recent study by the Locher group (IMBB) describes the development of camelid single-domain antibodies (nanobodies) that selectively ...

Genetics

New method for genetic analysis of resting human immune cells

CD4+ T cells are important parts of the immune system and play a key role in defending the body against pathogens. As they possess a great variety of defense mechanisms against HIV in their resting state, they are infected ...

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