Autism spectrum disorders

Scientists link genes to brain anatomy in autism

A team of scientists at the University of Cambridge has discovered that specific genes are linked to individual differences in brain anatomy in autistic children.

Oncology & Cancer

Gene fusion shifts cell activity into high gear, causing some cancer

The fusion of two adjacent genes can cause cancer by kicking mitochondria into overdrive and increasing the amount of fuel available for rampant cell growth, researchers at Columbia University Medical Center (CUMC) have discovered. ...

Genetics

Unexpected findings uncover new understanding of gene expression

Northwestern Medicine scientists have discovered that the catalytic activity of the fly enzyme Trr and mammalian MLL3/MLL4—members of the COMPASS family of proteins central to gene expression—is not required for proper ...

Neuroscience

When the brain's wiring breaks

Among all the bad things that can happen to the brain when it is severely jolted – in a car accident, for example – one of the most common and worrisome is axon damage. Axons are the long stalks that grow out of the bodies ...

Genetics

Gene variant activity is surprisingly variable between tissues

Every gene in almost every cell of the body is present in two variants called alleles—one from the mother, the other one from the father. In most cases, both alleles are active and transcribed by the cells into RNA. However, ...

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