A study performed by scientists at the Bellvitge Biomedical Research Institute and the Puigvert Foundation has identified a gene expression fingerprint associated with very low pregnancy rates in semen donors with normal ...
May 23, 2012
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Aging is a complex process that involves multiple metabolic and regulatory pathways. Previous studies have identified hundreds of genes whose deletion can significantly increase lifespan in model organisms. Yet, how these ...
Feb 23, 2017
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Three-dimensional (3D) culturing approaches help probe cancer stem-like cells (CSCs)-associated traits, chemoresistance, and cellular heterogeneity ex vivo. For instance, the culture of organoid-driven clinical cancer specimens ...
Oct 7, 2021
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(Medical Xpress)—Changes in an epigenetic mechanism that turns expression of genes on and off may be as important as genetic alterations in causing pediatric acute lymphoblastic leukemia (ALL), according to a study led ...
Jun 10, 2013
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PD-L2 protein expression in human tumors was associated with clinical response to pembrolizumab (Keytruda), an anti-PD-1 immunotherapy, independent of PD-L1 expression, in patients with head and neck squamous cell carcinoma ...
Jun 15, 2017
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Using a highly sensitive technology called NanoString, researchers have identified seven targets that could potentially be used to develop new immunotherapies for patients with metastatic melanoma, according to a study published ...
Sep 10, 2013
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In a unique project, researchers at the Icahn School of Medicine at Mount Sinai have crowdsourced the annotation and analysis of a large number of gene expression profiles from the National Center for Biotechnology Information's ...
Sep 26, 2016
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Figuring out how hundreds of different kinds of brain cells develop from their unique expression of thousands of genes promises to not only advance understanding of how the brain works in health, but also what goes wrong ...
Aug 23, 2023
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Data presented today at the European League Against Rheumatism Annual Congress (EULAR 2014) demonstrate the possibility of using biomarkers (developed from whole blood gene expression profiles) in children with juvenile idiopathic ...
Jun 13, 2014
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Scientists at Cedars-Sinai have developed a new way to identify which prostate cancer patients are likely to develop aggressive types of the disease even if their tumors at first appear to be lower risk. The new findings ...
Sep 7, 2016
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