(HealthDay)—The fibroblast growth factor receptor 3 (FGFR3) transforming acidic coiled-coil containing protein 3 (TACC3) (FT3) gene fusion recruits endogenous TACC3 away from the mitotic spindle, resulting in errors in ...
Sep 18, 2017
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There are many ways a gene can be altered and there are many genes that, when altered, can cause cancer. Testing individually for each possible alteration in every cancer-related gene is not feasible as it would require hundreds ...
Aug 30, 2017
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A study by the University of Warwick sheds new light on gene fusion in bladder and brain cancer.
Aug 30, 2017
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An assay that identifies a peculiar but important abnormality in cancer cells has been developed and validated by researchers at The Ohio State University Comprehensive Cancer Center – Arthur G. James Cancer Hospital and ...
Aug 14, 2017
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A team of scientists has demonstrated the mechanism by which ETO2-GLIS2, a gene fusion, promotes the development of an aggressive form of pediatric leukemia. The findings, published in Cancer Cell, also reveal an opportunity ...
May 9, 2017
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New research suggests a novel strategy to target a genetic anomaly that occurs in half of all prostate cancers.
Mar 23, 2017
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Two genetic mutations known to play a role in many solid cancers might also help explain why a subset of acute myeloid leukemia (AML) patients develop the disease, according to new research from The Ohio State University ...
Dec 7, 2016
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Despite years of research, cellular mechanisms contributing to cancers like esophageal adenocarcinoma have remained elusive. What has puzzled researchers was how genes in the healthy cells lining the esophagus turned the ...
Aug 26, 2016
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Researchers from the Medical Research Council (MRC) Centre for Regenerative Medicine at the University of Edinburgh have identified the cells responsible for a form of leukaemia that can develop while a baby is in the womb. ...
Jul 8, 2016
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The investigational anticancer therapeutic LOXO-101, which targets a family of proteins called neurotrophic tyrosine kinase receptors (NTRKs), was safe, tolerable, and showed signs of clinical activity in patients who had ...
Nov 9, 2015
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