A research paper titled "A novel group of genes that cause endocrine resistance in breast cancer identified by dynamic gene expression analysis" was recently published in Oncotarget.
Jun 8, 2022
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Inherited mutations in the BRCA1 gene can significantly increase a person's risk of breast and ovarian cancer—but not every mutation in the gene is harmful. To better equip patients and their doctors to understand and manage ...
Jun 3, 2022
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A 28-patient phase 1 gene therapy clinical trial for the degenerative retinal disease Leber hereditary optic neuropathy (LHON) found no significant safety concerns; however, treatment failed to improve or slow vision loss, ...
Jun 2, 2022
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The APOE4 gene is the most powerful genetic factor driving a person's risk for developing late-onset Alzheimer's disease.
Jun 1, 2022
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As an approach to personalized medicine, a new Nature Communications study proposes that "mutational footprints" of DNA repair are a promising predictive genetic marker for determining which tumors will respond to certain ...
May 26, 2022
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A common culprit of skin and respiratory infections, Staphylococcus aureus is highly unpredictable. Between 20 and 30 percent of people carry quiet colonies on their skin and in their nostrils, which seldom cause problems ...
May 19, 2022
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Breast cancer, COVID-19, and autism may seem unrelated, but they share some surprising connections. Some of the same genes that are mutated in breast cancer also get hijacked by COVID-19, and some other genes mutated in cancer ...
May 18, 2022
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The first bladder cancer drug targeting a cancer-driving gene mutation has been used relatively little despite its clear efficacy in a clinical trial, suggests a study from researchers at the Perelman School of Medicine at ...
May 12, 2022
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Inhibitors of the protein EZH2 are effective against cancers with SMARCB1 mutations such as rhabdoid tumors in children. However, these drugs are subject to treatment resistance. Scientists at St. Jude Children's Research ...
May 9, 2022
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Too many women are getting unnecessary mastectomies and other invasive procedures because of a knowledge gap about differences in cancer genes. A new study offers a path to closing the gap.
May 3, 2022
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