Study uncovers molecular role of gene linked to blood vessel formation
University of North Carolina researchers have discovered that disrupting a gene that acts as a regulatory switch to turn on other genes can keep blood vessels from forming and developing properly.
Medical research
Apr 29, 2013 |
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Key mechanism for a common form of Alzheimer's disease discovered
Scientists from the Icahn School of Medicine at Mount Sinai, in collaboration with researchers from Icelandic Heart Association, Sage Bionetworks, and other institutions, have discovered that a network of genes involved in ...
Alzheimer's disease & dementia
Apr 25, 2013 |
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Full wired: Planar cell polarity genes guide gut neurons
The enteric nervous system (ENS), the "little brain" that resides within the gut wall, governs motility, secretion, and blood flow in the human gastrointestinal tract. Failure of the ENS to develop normally leads to congenital ...
Medical research
Mar 08, 2013 |
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Epigenetics: Neurons remember because they move genes in space
How do neurons store information about past events? In the Nencki Institute of Experimental Biology of the Polish Academy of Sciences in Warsaw, a mechanism unknown previously of memory traces formation has ...
Neuroscience
Mar 07, 2013 |
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Study reveals molecular networks of mental health disorders
(Medical Xpress)—Early diagnosis and intervention for ADHD, autism and schizophrenia could be made possible after Australian scientists discovered the molecular networks in the brain showing psychiatric and developmental ...
Psychology & Psychiatry
Feb 27, 2013 |
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Less tau reduces seizures and sudden death in severe epilepsy
Deleting or reducing expression of a gene that carries the code for tau, a protein associated with Alzheimer's disease, can prevent seizures in a severe type of epilepsy linked to sudden death, said researchers at Baylor ...
Neuroscience
Jan 22, 2013 |
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Researchers discover new pathways that drive metastatic prostate cancer
Elevated levels of Cyclin D1b could function as a novel biomarker of lethal metastatic disease in prostate cancer patients, according to a pre-clinical study published ahead of print on December 21 in the Journal of Clinical In ...
Cancer
Dec 21, 2012 |
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World-first tissue study could re-shape future of advanced prostate cancer treatment
The first-ever comprehensive study of prostate cancer tissue has revealed a completely new gene network driving the disease in patients who have stopped responding to standard hormone treatment, according ...
Cancer
Dec 21, 2012 |
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Researchers devise a method for reprogramming cells in urine into neural progenitor cells
(Medical Xpress)—Researchers in China have developed a technique for reprogramming cells found in urine into neural progenitor cells that are capable of growing into neurons. In their paper published in ...
Medical research
Dec 10, 2012 |
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Schizophrenia genetic networks identified: Connection to autism found
Although schizophrenia is highly genetic in origin, the genes involved in the disorder have been difficult to identify. In the past few years, researchers have implicated several genes, but it is unclear how they act to produce ...
Neuroscience
Nov 11, 2012 |
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ASHG: 16 additional loci ID'd for coronary artery disease
(HealthDay)—Meta-analyses have identified an additional 16 loci with genome-wide significance for coronary artery disease (CAD), according to research presented at the annual meeting of the American Society ...
Genetics
Nov 09, 2012 |
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Putting a 'HEX' on muscle regeneration
A complex genetic regulatory network mediates the regeneration of adult skeletal muscles. In this issue of the Journal of Clinical Investigation, researchers at the State University of New York Downstate Medical Center in Bro ...
Medical research
Oct 01, 2012 |
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Specific regions of the hippocampus connected to discrete steps of task mastery, study finds
(Medical Xpress)—In a study published in Nature Neuroscience, neurobiologists from the Friedrich Miescher Institute for Biomedical Research have been linking synapse formation in the hippocampus to distinct learning steps. ...
Neuroscience
Oct 01, 2012 |
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Researchers determine how inflammatory cells function, setting stage for future remedies
A research team led by investigators at New York University and NYU School of Medicine has determined how cells that cause inflammatory ailments, such as Crohn's disease, multiple sclerosis, and arthritis, differentiate from ...
Inflammatory disorders
Sep 26, 2012 |
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Five genes have been found to determine human facial shapes
Five genes have been found to determine human facial shapes, as reported by researchers from the Netherlands, Germany, Canada, the United Kingdom, and Australia in the open-access journal PLOS Genetics.
Genetics
Sep 13, 2012 |
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