Genetics

Can a human microglial atlas guide brain disorder research?

Certain subtle differences in DNA sequences are known to raise the chances a person may develop Alzheimer's or Parkinson's disease. Some of these differences may work by altering the genetic activity of microglia, the brain's ...

Oncology & Cancer

Cell signaling targets in leukemia

Mutations in the enzyme IDH (isocitrate dehydrogenase) are found in 15–20% of acute myeloid leukemia (AML) cases. IDH mutations have been shown to impact cellular differentiation and DNA and histone methylation, but little ...

Oncology & Cancer

Solving mystery of rare cancers directly caused by HIV

For nearly a decade, scientists have known that HIV integrates itself into genes in cells that have the potential to cause cancer. And when this happens in animals with other retroviruses, those animals often develop cancer. ...

page 9 from 40