Oncology & Cancer

Modified killer T-cells wipe out leukemia: study

Three US cancer patients were brought back from the brink by a new therapy that turned their own immune cells into tumor killers, wiping out an advanced form of leukemia, researchers said Wednesday.

Neuroscience

First clinical trial of gene therapy for pain reported

In the first clinical trial of gene therapy for treatment of intractable pain, researchers from the University of Michigan Department of Neurology observed that the treatment appears to provide substantial pain relief.

Medications

Benefits of valoctocogene roxaparvovec persist in hemophilia A

For patients with hemophilia A, factor VIII activity and bleeding reduction persist at two years after gene transfer with valoctocogene roxaparvovec, which delivers a B-domain-deleted factor VIII coding sequence with an adeno-associated ...

Cardiology

ASH: High-dose gene transfer beneficial in severe hemophilia A

(HealthDay)—For men with severe hemophilia A, high-dose factor VIII gene transfer is associated with sustained normalization of factor VIII activity levels, according to a study published online Dec. 9 in the New England ...

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