Stemming the spread of cancer
Okayama University's Masaharu Seno and colleagues have demonstrated in vitro the development of cancer stem cells (CSCs) from a type of normal stem cell exposed to their hypothetical microenvironment of a ...
Cancer
Sep 21, 2012 |
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In lung cancer, smokers have 10 times more genetic damage than never-smokers
Lung cancer patients with a history of smoking have 10 times more genetic mutations in their tumors than those with the disease who have never smoked, according to a new study from Washington University School of Medicine ...
Cancer
Sep 13, 2012 |
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ENCODE project: Researchers catalogue functional elements of the genome
Most of the DNA alterations that are tied to disease do not alter protein-coding genes, but rather the "switches" that control them. Characterizing these switches is one of many goals of the ENCODE project ...
Genetics
Sep 05, 2012 |
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Team creates a unique mouse model for the study of aplastic anaemia
Aplastic anaemia is characterised by a reduction in the number of the bone marrow cells that go on to form the different cell types present in blood (essentially red blood cells, white blood cells and platelets). In most ...
Medical research
Aug 29, 2012 |
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Blood test could guide treatment for kidney cancer
A common enzyme that is easily detected in blood may predict how well patients with advanced kidney cancer will respond to a specific treatment, according to doctors at Duke Cancer Institute.
Cancer
Aug 13, 2012 |
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Existing drugs offer new treatment options for high-risk childhood leukemia subtype
Scientists have identified new genetic alterations underlying a high-risk subtype of the most common childhood cancer that could be effectively targeted with existing leukemia therapies.
Cancer
Aug 13, 2012 |
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Genetic variant is linked to obesity and insulin resistance
A large study in people at risk of diabetes has found a direct association between the presence of a small genetic alteration in a hormone receptor and increased body fat and insulin resistance. The results, to be presented ...
Genetics
Jun 26, 2012 |
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Gene sequencing project identifies potential drug targets in common childhood brain tumor
Researchers studying the genetic roots of the most common malignant childhood brain tumor have discovered missteps in three of the four subtypes of the cancer that involve genes already targeted for drug development.
Cancer
Jun 20, 2012 |
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Researchers create powerful new method to analyze genetic data
University of Texas Medical Branch at Galveston researchers have developed a powerful visual analytical approach to explore genetic data, enabling scientists to identify novel patterns of information that could be crucial ...
Genetics
Jun 12, 2012 |
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Distinct molecular subtype of prostate cancer identified
A collaborative expedition into the deep genetics of prostate cancer has uncovered a distinct subtype of the disease, one that appears to account for up to 15 percent of all cases, say researchers at Weill Cornell Medical ...
Genetics
May 20, 2012 |
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Molecular subtypes and genetic alterations may determine response to lung cancer therapy
Cancer therapies targeting specific molecular subtypes of the disease allow physicians to tailor treatment to a patient's individual molecular profile. But scientists are finding that in many types of cancer the molecular ...
Cancer
May 11, 2012 |
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Scientists find that chromosomal abnormalities are associated with aging and cancer
(Medical Xpress) -- Two new studies have found that large structural abnormalities in chromosomes, some of which have been associated with increased risk of cancer, can be detected in a small fraction of people without a ...
Genetics
May 08, 2012 |
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Higher maternal age predicts risk of autism
In a study published in the May 2012 issue of the Journal of the American Academy of Child and Adolescent Psychiatry, led by Mr. Sven Sandin, of the Karolinska Institutet, Sweden and King's College London, researchers analyz ...
Autism spectrum disorders
Apr 26, 2012 |
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Identifying acute myeloid leukemia gene mutations may indicate risk, best treatment
An international group of researchers, including those from Moffitt Cancer Center in Tampa, Fla., have published a paper in the March 14 issue of the New England Journal of Medicine reviewing the results of a study that a ...
Cancer
Mar 23, 2012 |
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Patients with rare diseases to get DNA sequenced at no charge
Rare genetic diseases, long overlooked because they affect relatively few people, are getting new attention. Scientists at Washington University School of Medicine in St. Louis are reaching out to patient ...
Genetics
Mar 01, 2012 |
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