News tagged with genetic model


Scientists identify important regulator for synapse stability and plasticity

(Medical Xpress)—Using the fruit fly as a model organism, neurobiologists from the Friedrich Miescher Institute for Biomedical Research have identified the L1-type CAM neuroglian as an important regulator ...

Neuroscience created Apr 25, 2013 | popularity 5 / 5 (1) | comments 0 | with audio podcast

Transgenic mice ready to fight obesity—and more

Scientists at the Nencki Institute of Experimental Biology of the Polish Academy of Sciences in Warsaw investigate mice with a very precisely modified genome. Because it is possible to turn off the Dicer ...

Genetics created Apr 25, 2013 | popularity not rated yet | comments 0

Expert discusses how BRAIN Initiative will affect neuroscience

Mapping the human brain, with its billions of neurons, is one of science's most elusive projects. But a new federal program—the $100 million Brain Research through Advancing Innovative Neurotechnologies (BRAIN) Initiative ...

Neuroscience created Apr 24, 2013 | popularity 5 / 5 (1) | comments 0

Fight control: Researchers link individual neurons to regulation of aggressive behavior in flies

(Medical Xpress)—Scientists have long pondered the roots of aggression—and ways to temper it. Now, new research is beginning to illuminate the cellular-level circuitry responsible for modulating aggression ...

Neuroscience created Apr 19, 2013 | popularity not rated yet | comments 0 | with audio podcast

New drug combination therapy developed to treat leukemia

A new, pre-clinical study by researchers at Virginia Commonwealth University Massey Cancer Center suggests that a novel drug combination could lead to profound leukemia cell death by disrupting the function of two major pro-survival ...

Cancer created Apr 17, 2013 | popularity 5 / 5 (1) | comments 0

Examining function of all genes in the zebrafish genome to benefit human health

Equipped with the zebrafish genome, researchers have designed a method to assay the function of each and every gene and to explore the effects genetic variation has on zebrafish. So far the team has generated one or more ...

Genetics created Apr 17, 2013 | popularity 5 / 5 (1) | comments 0 | with audio podcast

Study uncovers key factor in Alzheimer's progression

(Medical Xpress)—A new study from researchers at the University of Florida may have uncovered a critical factor that drives the relentless progression of Alzheimer's disease ― a discovery that could eventually slow its ...

Alzheimer's disease & dementia created Apr 16, 2013 | popularity 5 / 5 (1) | comments 0 | with audio podcast

Autism model in mice linked with genetics

For the first time, researchers have linked autism in a mouse model of the disease with abnormalities in specific regions of the animals' chromosomes. The regions contain genes associated with aberrant brain development and ...

Autism spectrum disorders created Apr 15, 2013 | popularity 4 / 5 (3) | comments 0 | with audio podcast

Study offers new approach for spinal muscular atrophy

Spinal muscular atrophy is a debilitating neuromuscular disease that in its most severe form is the leading genetic cause of infant death. By experimenting with an ALS drug in two very different animal models, researchers ...

Neuroscience created Apr 09, 2013 | popularity not rated yet | comments 0 | with audio podcast

Indo-Canadian student gives boost to cancer treatment (Update)

A Canadian high school student has improved an ineffective experimental cancer therapy with a simple tweak—pairing it with antibiotics—earning accolades Tuesday from a panel of eminent scientists.

Cancer created Apr 09, 2013 | popularity 5 / 5 (2) | comments 0

Rigosertib Phase 1 results lead to disease-focused Phase 2 development

Results of a phase 1 clinical trial reported at the American Association for Cancer Research (AACR) annual conference show that orally administered Rigosertib is well tolerated in patients with advanced solid tumors. This ...

Cancer created Apr 09, 2013 | popularity not rated yet | comments 0

K9 osteosarcoma samples identify drivers of metastasis in pediatric bone cancer

Human osteosarcoma samples are hard to come by, making the disease difficult to study. However, K9 bone cancer is genetically indistinguishable from the human form of the disease, and over 10,000 canine patients develop the ...

Cancer created Apr 09, 2013 | popularity not rated yet | comments 0

Alkaptonuria: New hope for treatment of rare genetic disease

(Medical Xpress)—Scientists at the University of Liverpool have found that a drug treatment administered at the earliest signs of a rare genetic disease could prevent the condition from developing in later ...

Arthritis & Rheumatism created Apr 04, 2013 | popularity 5 / 5 (2) | comments 0 | with audio podcast

Legal levels of atrazine alter neuroendocrine, reproductive genes in zebrafish

(Medical Xpress)—A Purdue University study found an agricultural herbicide alters reproductive and neuroendocrine genes during embryonic development in fish, a finding that will help establish a genetic ...

Medical research created Apr 03, 2013 | popularity 5 / 5 (2) | comments 1 | with audio podcast

Surprising findings in mitochondrial biology change long-standing ideas on the protein MTERF1

New findings in mitochondrial biology thoroughly change the idea scientists had for 20 years on the role and importance of the protein MTERF1. For the first time, Max Planck researcher Mügen Terzioglu and her colleagues ...

Medical research created Apr 02, 2013 | popularity 4 / 5 (1) | comments 0 | with audio podcast