Using genetic engineering technology, a team of scientists has established a pig model of Huntington's disease (HD), an inherited neurodegenerative disease. The researchers anticipate that the pigs could be a practical way ...
Mar 29, 2018
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Scientists studying the role of a protein complex in the normal development of the mouse brain unexpectedly created a mouse model that replicates clinical symptoms of patients with complex neurological disorders such as hyperactivity, ...
Mar 14, 2017
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University of Tokyo and RIKEN researchers have identified seven genes responsible for causing mice to stay awake or fall asleep based on a theoretical model of sleep and on experiments using 21 different genetically-modified ...
Mar 17, 2016
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Researchers have successfully disrupted a genetic chain of events in a mouse model of schizophrenia and reversed memory deficits, one of the disorder's most difficult-to-treat symptoms. This discovery—which builds upon ...
Feb 18, 2016
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Scientists at EPFL solve a longstanding problem with modeling Parkinson's disease in animals. Using newfound insights, they improve both cell and animal models for the disease, which can propel research and drug development.
Feb 1, 2016
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Many neurological disorders, such as Parkinson's disease and Alzheimer's disease, are marked by impaired motor skills. In addition, growing evidence suggests there's a link between some neurodegenerative diseases and body ...
Nov 11, 2015
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(Medical Xpress)—A particular kind of genetic interaction called synthetic dosage lethality (SDL) is a promising avenue for future cancer treatment, according to a study reported in the Proceedings of the National Academy ...
They're among the most powerful tools for shedding new light on cancer growth and evolution, but mathematical models of the disease for years have faced an either/or stand off.
Aug 26, 2015
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A molecule important in blood vessel formation and brain wiring is also essential for the onset of puberty, finds new research led by UCL and the University of Milan.
May 18, 2015
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An enzyme therapy may prevent skeletal abnormalities associated with the genetic disorder neurofibromatosis type-1, Vanderbilt investigators have discovered.
Aug 14, 2014
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